ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-19.PDB
Scoring matrix: FUS1_1PWT-19_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.51
Foldx random average score for Saccharomyces cerevisiae: 17.662

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1420221
Proteins after disorder filtering: 4576
 Total fragments: 71444
Proteins after pattern filtering: 2166
 Total fragments: 10535
Proteins after MINT filtering: 23
 Total fragments: 128


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.51

1.25

0.00

Best peptides

MRIRRGWFR

0.00

-2.25

-3.50

         
Interactors      
P36119

STTRPTVQP

16.97

-0.92

-2.17

TRPTVQPSN

17.31

-0.72

-1.97

PTVQPSNQS

17.45

0.78

-0.47

P53950

DSNPNGAPL

15.22

-1.59

-2.84

PNGAPLRRY

15.35

-1.87

-3.12

TPPAPLLPL

15.87

-2.03

-3.28

P40073

GYPQQQPSH

17.22

-0.23

-1.48

DGYPQQQPS

17.63

-0.16

-1.41

P24583

APLPPQPRK

13.53

-4.21

-5.46

LPPQPRKHD

14.46

-2.32

-3.57

PPQPRKHDK

15.03

-3.39

-4.64

P53947

PFNPIQDPF

16.92

-1.30

-2.55

FNPIQDPFT

16.95

0.86

-0.39

P34250

PKEPPARKS

12.39

-4.61

-5.86

ALYPKEPPA

14.99

-4.64

-5.89

SEPKPAYVP

16.95

-1.45

-2.70

P53046

PPTPKSAGH

14.31

-1.92

-3.17

LSTPPTPKS

16.83

-2.57

-3.82

Q12280

NVTPPLRPQ

14.25

-2.29

-3.54

PPLRPQSSS

14.61

-4.00

-5.25

SPSKPGNNN

15.12

-2.99

-4.24

P39732

RSPSVSPVR

16.59

-2.63

-3.88

SRSPSVSPV

17.32

-1.18

-2.43

TRHPSIAPP

17.64

-4.46

-5.71

P40091

PSHPHHNSR

13.73

-1.97

-3.22

MSSPASSPV

15.13

-2.14

-3.39

GMSSPASSP

15.87

-2.69

-3.94

P40450

SSSPKLFPR

12.81

-1.92

-3.17

PPLPNGLLS

12.89

-2.49

-3.74

PPLPDLFKT

13.11

-3.08

-4.33

P25376

DRPSSQPHL

14.71

-2.67

-3.92

PSSQPHLGY

16.06

-0.45

-1.70

SNDRPSSQP

17.18

-2.55

-3.80

P41832

GVIPPAPPM

13.04

-4.47

-5.72

PPPPMALFG

13.63

-2.70

-3.95

PPAPPMMPA

14.17

-3.11

-4.36

Q03466

PMAPDTFNV

13.84

-3.52

-4.77

VPMAPDTFN

14.01

-1.46

-2.71

P31374

SPERPSFRQ

12.66

-2.82

-4.07

KPPPPLDFE

14.23

-3.01

-4.26

PGTPVFPNL

14.28

-2.30

-3.55

P32917

DYLPQHPHR

12.26

-2.10

-3.35

SRFPPYSPL

13.08

-3.10

-4.35

IPPKVAPFG

14.45

-1.79

-3.04

P40020

PPLTPEKNL

13.23

-2.96

-4.21

RVLPPLPFP

13.73

-4.86

-6.11

ISLPPYLSP

13.99

-4.07

-5.32

P16892

NDEPEGEPI

14.81

-1.48

-2.73

P40210

EVDPTEPQT

16.46

-0.39

-1.64

DPTEPQTND

16.66

-0.97

-2.22

Q12114

KSEPVGTPN

15.90

-1.67

-2.92

P21268

LSKPISPPP

17.34

-4.31

-5.56

Q12753

MIKPKGRPS

9.68

-3.68

-4.93

PRMPKTGSR

11.10

-3.13

-4.38

INSPRMPKT

13.52

-3.35

-4.60

P14681

PSDEPEYPP

16.26

-2.15

-3.40

 


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