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Matrix information:
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ADAN-name: FUS1_1PWT-17.PDB
Scoring matrix: FUS1_1PWT-17_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.95
Foldx random average score for Saccharomyces cerevisiae: 15.873 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3207038
Proteins after random average filtering: 7178
Total fragments: 1530077
Proteins after disorder filtering: 4638
Total fragments: 92349
Proteins after pattern filtering: 2059
Total fragments: 8202
Proteins after MINT filtering: 23
Total fragments: 114
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
15.95
|
5.31 |
0.00 |
| Best peptides |
RRFEKGFWR |
0.00
|
2.17 |
-3.14 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P36119 |
PTVQPSNQS |
13.80
|
3.62 |
-1.69 |
|
TRPTVQPSN |
14.30
|
0.58 |
-4.73 |
| P53950 |
PNGAPLRRY |
11.28
|
0.08 |
-5.23 |
|
APLLPLPSL |
11.68
|
-0.32 |
-5.63 |
|
APNPSIPSA |
13.97
|
2.02 |
-3.29 |
| P40073 |
GYPQQQPSH |
13.11
|
0.30 |
-5.01 |
| P24583 |
LPPQPRKHD |
12.02
|
-1.09 |
-6.40 |
|
APLPPQPRK |
12.50
|
0.16 |
-5.15 |
|
RANAPLPPQ |
12.75
|
-0.86 |
-6.17 |
| P53947 |
PFNPIQDPF |
15.65
|
2.28 |
-3.03 |
| P34250 |
PKEPPARKS |
13.62
|
1.01 |
-4.30 |
|
SSNPDLPTA |
13.71
|
2.51 |
-2.80 |
|
PSNPPSSGN |
14.82
|
2.14 |
-3.17 |
| P53046 |
LSTPPTPKS |
12.75
|
-0.13 |
-5.44 |
|
PPTPKSAGH |
13.45
|
1.56 |
-3.75 |
|
TPPTPKSAG |
15.79
|
1.92 |
-3.39 |
| Q12280 |
NVTPPLRPQ |
12.64
|
0.15 |
-5.16 |
|
VTPPLRPQS |
12.80
|
2.74 |
-2.57 |
|
PLRPQSSSK |
13.17
|
2.18 |
-3.13 |
| P39732 |
RSPSVSPVR |
12.89
|
1.47 |
-3.84 |
|
PSPSPTSSA |
13.30
|
2.38 |
-2.93 |
|
SSPSPSPTS |
14.70
|
2.99 |
-2.32 |
| P40091 |
PSHPHHNSR |
10.28
|
1.48 |
-3.83 |
|
SQNPSHPHH |
13.49
|
0.51 |
-4.80 |
|
TWDPSSPSS |
14.75
|
2.12 |
-3.19 |
| P40450 |
SSSPKLFPR |
10.33
|
0.78 |
-4.53 |
|
PPLPESLSM |
11.66
|
0.07 |
-5.24 |
|
PPPPPLPQS |
12.69
|
0.94 |
-4.37 |
| P25376 |
PSSQPHLGY |
11.61
|
2.16 |
-3.15 |
|
DRPSSQPHL |
13.77
|
0.15 |
-5.16 |
| P41832 |
PPPPPLPSV |
12.84
|
0.75 |
-4.56 |
|
PPPPMALFG |
13.16
|
1.68 |
-3.63 |
|
PPPPPVPAK |
14.70
|
0.13 |
-5.18 |
| Q03466 |
VPMAPDTFN |
14.74
|
0.80 |
-4.51 |
| P31374 |
SPERPSFRQ |
10.45
|
-0.02 |
-5.33 |
|
KPPPPLDFE |
11.07
|
-0.12 |
-5.43 |
|
NISPERPSF |
11.84
|
0.22 |
-5.09 |
| P32917 |
LPQHPHRTS |
11.04
|
3.32 |
-1.99 |
|
RFPPYSPLL |
12.48
|
0.03 |
-5.28 |
|
DYLPQHPHR |
12.87
|
-0.22 |
-5.53 |
| P40020 |
LPPYLSPQN |
11.17
|
1.52 |
-3.79 |
|
RPPPLTPEK |
12.89
|
0.92 |
-4.39 |
|
MSLPVTPVK |
13.15
|
-0.48 |
-5.79 |
| P16892 |
NDEPEGEPI |
14.80
|
1.38 |
-3.93 |
| P40210 |
DEVDPTEPQ |
15.04
|
1.25 |
-4.06 |
|
DPTEPQTND |
15.77
|
0.58 |
-4.73 |
| Q12114 |
KSEPVGTPN |
14.34
|
2.02 |
-3.29 |
| P21268 |
KPISPPPSL |
15.46
|
0.79 |
-4.52 |
| Q12753 |
PRMPKTGSR |
9.44
|
-1.08 |
-6.39 |
|
MIKPKGRPS |
10.22
|
-0.69 |
-6.00 |
|
PQSPPLSSM |
10.54
|
0.16 |
-5.15 |
| P14681 |
EPEYPPLNL |
15.78
|
-0.25 |
-5.56 |
|
