ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-14.PDB
Scoring matrix: FUS1_1PWT-14_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.47
Foldx random average score for Saccharomyces cerevisiae: 12.846

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1325079
Proteins after disorder filtering: 4315
 Total fragments: 52122
Proteins after pattern filtering: 1661
 Total fragments: 5064
Proteins after MINT filtering: 16
 Total fragments: 52


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.47

-0.66

0.00

Best peptides

RWKRILKYF

0.00

-0.20

0.46

         
Interactors      
Q12280

PPLRPQSSS

11.28

-1.65

-0.99

GSPSKPGNN

12.67

0.87

1.53

P31374

ISPERPSFR

8.29

-1.08

-0.42

EQPRLPSTA

10.41

0.19

0.85

KPPPPLDFE

10.49

-1.58

-0.92

P36119

RPTVQPSNQ

9.56

-1.76

-1.10

TRPTVQPSN

11.76

-1.96

-1.30

P24583

RANAPLPPQ

12.08

-2.66

-2.00

LPPQPRKHD

12.40

-0.52

0.14

P39732

RSPSVSPVR

8.78

0.45

1.11

HPSIAPPSK

11.23

-2.12

-1.46

RHPSIAPPS

11.77

-2.28

-1.62

P40091

QNPSHPHHN

10.78

-0.74

-0.08

SPASSPVTW

11.16

-1.05

-0.39

P40450

PKLFPRLSS

11.14

-2.55

-1.89

SSSPKLFPR

12.11

-1.74

-1.08

APPPLPDLF

12.18

-1.26

-0.60

P32917

IPPKVAPFG

10.34

-1.54

-0.88

YSPLLPPFG

11.52

-0.43

0.23

NIPPKVAPF

12.34

-2.63

-1.97

P25376

RPSSQPHLG

10.10

-0.70

-0.04

PSSQPHLGY

12.72

-1.41

-0.75

P40020

LTPESPLNR

11.11

-0.37

0.29

APSIPVEHS

11.86

-2.65

-1.99

PPPLTPEKN

11.92

-2.61

-1.95

P41832

PPPPPMALF

11.48

-3.57

-2.91

P53947

ASPFNPIQD

12.65

0.80

1.46

P34250

KPAYVPPED

10.70

-1.06

-0.40

KKPSNPPSS

11.03

-1.47

-0.81

LYPKEPPAR

11.24

-1.24

-0.58

Q12753

NSPRMPKTG

10.31

-0.83

-0.17

PKGRPSTTC

11.46

-1.78

-1.12

SINSPRMPK

12.22

-2.15

-1.49

Q03466

SVPMAPDTF

10.17

-3.31

-2.65

P53950

PNGAPLRRY

12.60

-1.88

-1.22

SNPNGAPLR

12.69

-0.31

0.35

 


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