ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1PWT-12.PDB
Scoring matrix: FUS1_1PWT-12_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.43
Foldx random average score for Saccharomyces cerevisiae: 8.822

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1355249
Proteins after disorder filtering: 4539
 Total fragments: 70014
Proteins after pattern filtering: 2098
 Total fragments: 10709
Proteins after MINT filtering: 21
 Total fragments: 161


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.43

-0.86

0.00

Best peptides

HSWMPWRK

0.00

-2.20

-1.34

         
Interactors      
Q12280

NVTPPLRP

6.32

-3.83

-2.97

VTPPLRPQ

7.41

-2.48

-1.62

SGSPSKPG

7.66

-2.76

-1.90

P31374

PERPSFRQ

4.63

-3.79

-2.93

KTKPPPPL

6.39

-3.74

-2.88

NISPERPS

6.91

-2.76

-1.90

P36119

TTRPTVQP

8.02

-2.96

-2.10

TRPTVQPS

8.56

-2.15

-1.29

P40073

DGYPQQQP

6.95

-3.46

-2.60

GYPQQQPS

8.62

-1.86

-1.00

P24583

APLPPQPR

6.14

-4.65

-3.79

PLPPQPRK

6.84

-2.50

-1.64

RANAPLPP

7.95

-4.30

-3.44

P39732

PSVSPVRT

5.61

-3.56

-2.70

TRHPSIAP

7.01

-4.09

-3.23

SRSPSVSP

8.16

-2.59

-1.73

P21268

NLSKPISP

8.21

-2.45

-1.59

LSKPISPP

8.33

-2.44

-1.58

PISPPPSL

8.34

-1.96

-1.10

P40091

SQNPSHPH

6.31

-3.60

-2.74

PSHPHHNS

7.19

-3.40

-2.54

VTWDPSSP

7.97

-1.75

-0.89

P40450

GAVPPPPP

6.32

-3.35

-2.49

PQLPPPPP

6.74

-3.67

-2.81

SSPKLFPR

6.93

-2.86

-2.00

P32917

SRFPPYSP

5.27

-4.34

-3.48

TDYLPQHP

6.09

-0.21

0.65

DYLPQHPH

6.67

-3.61

-2.75

P25376

PSSQPHLG

7.85

-2.09

-1.23

DRPSSQPH

8.09

-2.98

-2.12

P40020

RVLPPLPF

6.56

-5.21

-4.35

SRVLPPLP

7.23

-2.72

-1.86

TSAPSIPV

7.47

-2.85

-1.99

P41832

SSQPPPPP

7.31

-3.40

-2.54

ETPPPPPL

7.58

-2.78

-1.92

GDSPAPPP

7.69

-2.21

-1.35

P16892

EGEPIPPS

8.41

-2.40

-1.54

Q03466

SSVPMAPD

7.80

-2.47

-1.61

GSSVPMAP

8.45

-2.31

-1.45

P14681

SDEPEYPP

6.55

-2.89

-2.03

PEYPPLNL

7.38

-3.94

-3.08

PSDEPEYP

8.61

-0.35

0.51

P53046

LSTPPTPK

8.00

-2.23

-1.37

STPPTPKS

8.30

-2.56

-1.70

P53947

PFNPIQDP

7.84

-3.96

-3.10

SPFNPIQD

8.15

-3.18

-2.32

PIQDPFTD

8.68

-2.96

-2.10

Q12753

HRYPPMAP

6.01

-4.15

-3.29

INSPRMPK

6.87

-3.64

-2.78

MIKPKGRP

7.02

-2.39

-1.53

P34250

SKKPSNPP

6.58

-3.84

-2.98

PKEPPARK

6.65

-3.34

-2.48

SSNPDLPT

6.94

-4.63

-3.77

P53950

APNPSIPS

7.43

-3.73

-2.87

PLLPLPSL

8.05

-2.53

-1.67

GSNTPPAP

8.24

-2.58

-1.72

 


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