ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-8.PDB
Scoring matrix: FUS1_1OV32-8_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.25
Foldx random average score for Saccharomyces cerevisiae: 10.529

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1272527
Proteins after disorder filtering: 4309
 Total fragments: 62856
Proteins after pattern filtering: 2107
 Total fragments: 11942
Proteins after MINT filtering: 21
 Total fragments: 178


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.25

1.38

0.00

Best peptides

RRRWIHPF

0.00

-4.25

-5.63

         
Interactors      
Q12280

VTPPLRPQ

8.18

-3.11

-4.49

TPPLRPQS

8.52

-2.87

-4.25

GSPSKPGN

8.81

-1.86

-3.24

P36119

TRPTVQPS

7.36

-1.32

-2.70

TTRPTVQP

9.66

-1.39

-2.77

P53046

STPPTPKS

10.10

-2.32

-3.70

TPPTPKSA

10.18

-0.80

-2.18

P40073

YPQQQPSH

10.51

-2.28

-3.66

P24583

ANAPLPPQ

8.24

-3.90

-5.28

PLPPQPRK

8.27

-3.60

-4.98

APLPPQPR

8.91

-3.17

-4.55

P39732

TRHPSIAP

7.15

-1.95

-3.33

RHPSIAPP

7.79

-4.66

-6.04

SRSPSVSP

9.04

-2.09

-3.47

P21268

LSKPISPP

7.30

-2.42

-3.80

SKPISPPP

8.32

-4.15

-5.53

KPISPPPS

9.75

-2.98

-4.36

P40091

QNPSHPHH

8.46

-1.69

-3.07

PSHPHHNS

10.03

-0.11

-1.49

SQNPSHPH

10.17

0.14

-1.24

P40450

SSPKLFPR

6.65

-3.38

-4.76

APPPLPDL

6.93

-4.50

-5.88

SPKLFPRL

7.33

-3.90

-5.28

P32917

YSPLLPPF

6.00

-5.30

-6.68

RFPPYSPL

6.99

-0.94

-2.32

SRFPPYSP

7.13

-3.40

-4.78

P25376

DRPSSQPH

7.13

-4.50

-5.88

RPSSQPHL

9.61

-2.39

-3.77

P40020

DRPPPLTP

7.23

-3.87

-5.25

PPLPFPLY

7.27

-5.04

-6.42

VLPPLPFP

7.41

-4.75

-6.13

P41832

PPPPMALF

6.93

-2.82

-4.20

PPPPVPAK

7.37

-3.49

-4.87

PPPPPPPM

7.69

-3.22

-4.60

P16892

GEPIPPSF

8.25

-2.80

-4.18

EGEPIPPS

9.98

-2.75

-4.13

P53947

FNPIQDPF

8.72

-0.25

-1.63

PFNPIQDP

9.26

-3.95

-5.33

ASPFNPIQ

9.85

-1.42

-2.80

Q12114

EPVGTPNI

9.82

-2.40

-3.78

P31374

ISPERPSF

6.27

-5.22

-6.60

KKPGTPVF

7.08

-4.03

-5.41

KPPPPLDF

7.59

-3.27

-4.65

Q12753

HRYPPMAP

6.81

-4.42

-5.80

INSPRMPK

7.20

-2.66

-4.04

PRMPKTGS

7.24

-1.93

-3.31

P34250

YPKEPPAR

8.15

-3.44

-4.82

KKPSNPPS

8.50

-2.87

-4.25

ALYPKEPP

8.58

-1.40

-2.78

P14681

DEPEYPPL

8.57

-1.63

-3.01

DPSDEPEY

10.30

-3.28

-4.66

P53950

PNPSIPSA

7.69

-3.87

-5.25

PLLPLPSL

8.16

-5.32

-6.70

PAPLLPLP

8.56

-4.27

-5.65

 


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