ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-7.PDB
Scoring matrix: FUS1_1OV32-7_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 14.95
Foldx random average score for Saccharomyces cerevisiae: 11.913

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1373281
Proteins after disorder filtering: 4612
 Total fragments: 77465
Proteins after pattern filtering: 2097
 Total fragments: 10975
Proteins after MINT filtering: 22
 Total fragments: 137


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

14.95

-0.92

0.00

Best peptides

MRRRNKRR

0.00

-5.29

-4.38

         
Interactors      
P36119

PTVQPSNQ

10.70

-2.47

-1.56

P53950

PNGAPLRR

7.70

-6.26

-5.34

SNTPPAPL

10.42

-2.95

-2.04

PNPSIPSA

10.76

-1.16

-0.24

P40073

PQQQPSHT

10.86

-3.05

-2.13

P24583

LPPQPRKH

7.26

-5.52

-4.60

PLPPQPRK

8.76

-5.83

-4.92

ANAPLPPQ

9.08

-4.65

-3.74

P53947

ASPFNPIQ

6.36

-3.98

-3.06

P34250

PKEPPARK

7.14

-8.40

-7.49

KKPSNPPS

7.52

-3.32

-2.40

YPKEPPAR

8.39

-3.99

-3.08

P53046

LSTPPTPK

9.59

-4.10

-3.18

Q12280

VTPPLRPQ

8.98

-2.59

-1.67

YSGSPSKP

9.92

-4.67

-3.75

GSPSKPGN

10.45

-1.21

-0.29

P39732

PSVSPVRT

9.09

-5.38

-4.46

SSPSPSPT

10.72

-1.81

-0.90

RSPSVSPV

11.36

-0.89

0.03

P40091

QNPSHPHH

7.73

-1.81

-0.90

NPSHPHHN

10.92

-4.11

-3.20

PASSPVTW

11.76

-1.96

-1.04

P40450

PKLFPRLS

8.37

-6.50

-5.59

PPPPPLPQ

9.43

-3.65

-2.73

SSPKLFPR

9.97

-3.44

-2.52

P25376

PSSQPHLG

9.57

-3.96

-3.04

DRPSSQPH

10.01

-1.25

-0.33

RPSSQPHL

10.61

-3.82

-2.90

P41832

PPPPPPMA

9.04

-5.36

-4.45

IPPAPPMM

9.11

-5.21

-4.29

PPPPPPPM

10.32

-4.42

-3.50

Q03466

PMAPDTFN

11.32

-2.01

-1.09

P31374

SPERPSFR

7.41

-6.04

-5.13

TKPPPPLD

8.75

-5.14

-4.22

KTKPPPPL

9.12

-4.37

-3.46

P32917

YLPQHPHR

7.98

-2.59

-1.67

LPQHPHRT

9.37

-4.81

-3.89

FPPYSPLL

9.89

-3.03

-2.11

P40020

EPTSPTRQ

7.72

-3.92

-3.00

PLPFPLYD

8.75

-4.53

-3.62

LPPYLSPQ

8.77

-3.27

-2.36

P16892

PNDEPEGE

11.55

-2.75

-1.84

P40210

DPTEPQTN

11.67

-1.96

-1.04

P21268

KPISPPPS

9.59

-3.74

-2.83

PISPPPSL

11.61

-3.11

-2.19

Q12753

NSPRMPKT

8.60

-2.87

-1.96

MIKPKGRP

8.83

-5.61

-4.70

INSPRMPK

9.42

-3.84

-2.92

P14681

EPEYPPLN

9.29

-5.03

-4.12

PSDEPEYP

10.54

-4.26

-3.34

DEPEYPPL

10.58

-1.35

-0.44

 


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