ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-4.PDB
Scoring matrix: FUS1_1OV32-4_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.37
Foldx random average score for Saccharomyces cerevisiae: 24.763

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1329232
Proteins after disorder filtering: 4564
 Total fragments: 102520
Proteins after pattern filtering: 2278
 Total fragments: 18306
Proteins after MINT filtering: 23
 Total fragments: 260


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.37

10.79

0.00

Best peptides

RRPRRPRPRR

0.00

-3.42

-14.21

         
Interactors      
P36119

SSTTRPTVQP

20.31

-1.01

-11.80

RPTVQPSNQS

20.54

0.14

-10.65

TRPTVQPSNQ

21.55

-3.37

-14.16

P53950

SNPNGAPLRR

17.02

-3.79

-14.58

IFDSNPNGAP

17.06

-2.30

-13.09

VVAPNPSIPS

18.52

-1.38

-12.17

P40073

QFDGYPQQQP

17.85

-2.69

-13.48

P24583

NAPLPPQPRK

14.58

-4.66

-15.45

ANAPLPPQPR

18.32

-0.69

-11.48

ERANAPLPPQ

18.86

-1.89

-12.68

P53947

ASPFNPIQDP

23.00

-1.58

-12.37

NPIQDPFTDN

24.51

1.03

-9.76

FNPIQDPFTD

24.59

1.18

-9.61

P34250

LYPKEPPARK

14.90

-2.76

-13.55

YHSKKPSNPP

16.09

-3.11

-13.90

KKPSNPPSSG

20.29

0.89

-9.90

P53046

NQLSTPPTPK

18.86

-0.50

-11.29

STPPTPKSAG

22.38

-0.24

-11.03

QLSTPPTPKS

23.11

-3.98

-14.77

Q12280

TAPASPEEPK

18.11

-1.85

-12.64

AYSGSPSKPG

18.42

-2.16

-12.95

NINTAPASPE

19.78

-0.65

-11.44

P39732

NSTRHPSIAP

16.73

-0.09

-10.88

NSSRSPSVSP

16.87

1.74

-9.05

RHPSIAPPSK

17.06

-0.64

-11.43

P40091

QNPSHPHHNS

18.57

-0.23

-11.02

FGMSSPASSP

19.36

0.45

-10.34

PVTWDPSSPS

19.48

-1.22

-12.01

P40450

SPKLFPRLSS

17.31

-1.79

-12.58

PAPPLPNGLL

17.89

-1.99

-12.78

AVPPPPPPPP

18.13

-2.14

-12.93

P25376

GSNDRPSSQP

20.27

-0.04

-10.83

SNDRPSSQPH

21.00

-1.20

-11.99

RPSSQPHLGY

21.54

-2.92

-13.71

P41832

VIPPAPPMMP

17.95

-2.79

-13.58

SQPPPPPPPP

18.19

-1.48

-12.27

TTGDSPAPPP

19.83

-1.70

-12.49

Q03466

SVPMAPDTFN

18.05

-1.43

-12.22

SGSSVPMAPD

21.80

-0.04

-10.83

SSVPMAPDTF

24.09

1.46

-9.33

P31374

FRKTKPPPPL

16.19

-3.13

-13.92

EQPRLPSTAS

16.44

-0.22

-11.01

RKTKPPPPLD

17.17

-1.83

-12.62

P32917

SRFPPYSPLL

14.42

-5.42

-16.21

PQSRFPPYSP

17.79

-1.57

-12.36

STDYLPQHPH

19.76

-1.75

-12.54

P40020

SFDRPPPLTP

16.23

-3.40

-14.19

SRVLPPLPFP

17.71

-1.72

-12.51

PHSIPFSVLS

18.69

-3.11

-13.90

P16892

TYHDPNDEPE

19.37

-1.66

-12.45

QTYHDPNDEP

20.39

-0.30

-11.09

EPEGEPIPPS

22.87

0.24

-10.55

P40210

VDPTEPQTND

23.10

1.75

-9.04

HDEVDPTEPQ

23.21

1.52

-9.27

Q12114

GHETAPVSPV

21.24

-2.12

-12.91

KSEPVGTPNI

22.49

-0.78

-11.57

SGHETAPVSP

24.03

1.01

-9.78

P21268

PISPPPSLKK

16.50

-2.52

-13.31

SKPISPPPSL

18.80

-0.59

-11.38

KPISPPPSLK

19.60

-1.79

-12.58

Q12753

QSINSPRMPK

14.79

-1.86

-12.65

MIKPKGRPST

15.69

-4.24

-15.03

GRNDLPDTSP

15.96

-2.84

-13.63

P14681

SDEPEYPPLN

22.26

-0.29

-11.08

DEPEYPPLNL

22.77

-0.26

-11.05

YHDPSDEPEY

22.92

0.96

-9.83

 


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