ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-28.PDB
Scoring matrix: FUS1_1OV32-28_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.7
Foldx random average score for Saccharomyces cerevisiae: 13.857

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1644925
Proteins after disorder filtering: 4438
 Total fragments: 78172
Proteins after pattern filtering: 2069
 Total fragments: 10706
Proteins after MINT filtering: 22
 Total fragments: 154


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.70

3.66

0.00

Best peptides

RRRLYRHRRR

0.00

-6.86

-10.52

         
Interactors      
P36119

TRPTVQPSNQ

11.11

-3.52

-7.18

RPTVQPSNQS

11.80

-3.73

-7.39

P53950

SNPNGAPLRR

11.25

-3.10

-6.76

PAPLLPLPSL

11.66

-5.57

-9.23

DSNPNGAPLR

11.95

-4.08

-7.74

P53046

TPPTPKSAGH

12.41

-3.38

-7.04

LSTPPTPKSA

12.50

-2.88

-6.54

STPPTPKSAG

12.97

-1.78

-5.44

P24583

NAPLPPQPRK

7.89

-5.38

-9.04

LPPQPRKHDK

9.69

-4.89

-8.55

APLPPQPRKH

10.75

-5.68

-9.34

P53947

NPIQDPFTDN

13.06

-2.44

-6.10

FNPIQDPFTD

13.42

-0.29

-3.95

P34250

KKPSNPPSSG

8.43

-4.38

-8.04

LYPKEPPARK

9.60

-2.63

-6.29

YPKEPPARKS

9.77

-4.04

-7.70

Q03466

SVPMAPDTFN

13.52

-4.15

-7.81

Q12280

YSGSPSKPGN

8.99

-2.88

-6.54

NVTPPLRPQS

11.22

-4.20

-7.86

PPLRPQSSSK

11.28

-3.97

-7.63

P39732

RHPSIAPPSK

6.97

-5.92

-9.58

RSPSVSPVRT

11.61

-2.49

-6.15

PSIAPPSKLN

13.07

-3.59

-7.25

P40091

QNPSHPHHNS

9.13

-2.34

-6.00

NPSHPHHNSR

10.06

-1.46

-5.12

P40450

TPPAPPLPNG

8.95

-6.28

-9.94

PPPPPPLPQS

9.54

-5.39

-9.05

PPLPDLFKTK

9.94

-3.39

-7.05

P25376

RPSSQPHLGY

9.18

-5.88

-9.54

DRPSSQPHLG

12.45

-2.85

-6.51

P41832

PPPPPPMALF

8.69

-7.08

-10.74

PPPPPPVPAK

9.68

-5.47

-9.13

PPPPMALFGK

9.75

-5.98

-9.64

P31374

KPGTPVFPNL

8.42

-6.54

-10.20

RKTKPPPPLD

8.71

-8.36

-12.02

TKPPPPLDFE

8.98

-6.17

-9.83

P32917

TDYLPQHPHR

7.68

-3.73

-7.39

YLPQHPHRTS

7.95

-2.51

-6.17

SPLLPPFGLS

9.20

-4.42

-8.08

P40020

RPPPLTPEKN

9.18

-8.30

-11.96

YLTPESPLNR

9.38

-4.62

-8.28

PLPFPLYDEK

10.06

-4.98

-8.64

P16892

YHDPNDEPEG

11.05

-1.40

-5.06

PEGEPIPPSF

12.60

-3.89

-7.55

P40210

PTEPQTNDSE

13.84

-1.86

-5.52

Q12114

KSEPVGTPNI

12.93

-2.94

-6.60

P21268

KPISPPPSLK

6.53

-6.51

-10.17

PISPPPSLKK

10.47

-4.82

-8.48

Q12753

IPQSPPLSSM

7.90

-5.71

-9.37

SPRMPKTGSR

10.28

-5.06

-8.72

PRMPKTGSRQ

10.71

-3.85

-7.51

P14681

EPEYPPLNLD

10.71

-4.74

-8.40

DEPEYPPLNL

12.70

-4.65

-8.31

 


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