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Matrix information:
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ADAN-name: FUS1_1OV32-27.PDB
Scoring matrix: FUS1_1OV32-27_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 16.22
Foldx random average score for Saccharomyces cerevisiae: 14.618 Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
Proteins belonging to other specie: 0
Nš of interactions described: 47
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
Total fragments: 3207038
Proteins after random average filtering: 7178
Total fragments: 1272273
Proteins after disorder filtering: 4458
Total fragments: 78965
Proteins after pattern filtering: 2275
Total fragments: 16580
Proteins after MINT filtering: 23
Total fragments: 255
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAAA |
16.22
|
-3.01 |
0.00 |
| Best peptides |
YDRPMHRRR |
0.00
|
-7.38 |
-4.37 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P36119 |
TTRPTVQPS |
9.40
|
-4.00 |
-0.99 |
|
STTRPTVQP |
13.94
|
-4.10 |
-1.09 |
| P53950 |
PNGAPLRRY |
10.02
|
-8.00 |
-4.99 |
|
VVAPNPSIP |
11.13
|
-2.67 |
0.34 |
|
NTPPAPLLP |
11.15
|
-5.35 |
-2.34 |
| P40073 |
FDGYPQQQP |
9.86
|
-5.45 |
-2.44 |
|
YPQQQPSHT |
11.32
|
-5.30 |
-2.29 |
|
DGYPQQQPS |
11.51
|
-3.69 |
-0.68 |
| P24583 |
APLPPQPRK |
9.42
|
-6.43 |
-3.42 |
|
PLPPQPRKH |
9.76
|
-4.29 |
-1.28 |
|
PPQPRKHDK |
11.13
|
-4.23 |
-1.22 |
| P53947 |
NPIQDPFTD |
12.51
|
-4.22 |
-1.21 |
|
PFNPIQDPF |
12.71
|
-2.58 |
0.43 |
|
SPFNPIQDP |
14.45
|
-4.01 |
-1.00 |
| P34250 |
YHSKKPSNP |
9.26
|
-5.09 |
-2.08 |
|
YPKEPPARK |
9.37
|
-8.08 |
-5.07 |
|
PKEPPARKS |
9.47
|
-4.56 |
-1.55 |
| P53046 |
LSTPPTPKS |
11.17
|
-3.14 |
-0.13 |
|
STPPTPKSA |
11.48
|
-3.56 |
-0.55 |
|
PPTPKSAGH |
13.27
|
-3.78 |
-0.77 |
| Q12280 |
NVTPPLRPQ |
6.59
|
-6.24 |
-3.23 |
|
YSGSPSKPG |
10.97
|
-5.18 |
-2.17 |
|
VTPPLRPQS |
12.24
|
-5.11 |
-2.10 |
| P39732 |
STRHPSIAP |
11.57
|
-3.63 |
-0.62 |
|
TRHPSIAPP |
11.67
|
-3.86 |
-0.85 |
|
SSSPSPSPT |
12.08
|
-2.91 |
0.10 |
| P40091 |
NPSHPHHNS |
8.81
|
-4.35 |
-1.34 |
|
MSSPASSPV |
10.16
|
-3.74 |
-0.73 |
|
PSHPHHNSR |
10.36
|
-3.89 |
-0.88 |
| P40450 |
SSSPKLFPR |
7.89
|
-5.26 |
-2.25 |
|
LPPPPPPPP |
9.68
|
-5.13 |
-2.12 |
|
VPPPPPPPP |
9.81
|
-4.90 |
-1.89 |
| P25376 |
NDRPSSQPH |
9.04
|
-4.89 |
-1.88 |
|
RPSSQPHLG |
12.67
|
-6.36 |
-3.35 |
|
SNDRPSSQP |
12.97
|
-2.83 |
0.18 |
| P41832 |
TPPPPPLPS |
8.64
|
-5.84 |
-2.83 |
|
PPAPPMMPA |
9.70
|
-5.62 |
-2.61 |
|
QPPPPPPPP |
9.98
|
-3.98 |
-0.97 |
| Q03466 |
PMAPDTFNV |
11.80
|
-2.61 |
0.40 |
|
SSVPMAPDT |
11.86
|
-3.35 |
-0.34 |
|
VPMAPDTFN |
12.74
|
-3.59 |
-0.58 |
| P31374 |
SPERPSFRQ |
8.40
|
-8.89 |
-5.88 |
|
RKTKPPPPL |
9.51
|
-5.89 |
-2.88 |
|
KPPPPLDFE |
9.70
|
-3.75 |
-0.74 |
| P32917 |
YLPQHPHRT |
8.47
|
-8.55 |
-5.54 |
|
LPQHPHRTS |
8.99
|
-6.70 |
-3.69 |
|
SRFPPYSPL |
9.39
|
-4.24 |
-1.23 |
| P40020 |
RVLPPLPFP |
8.61
|
-6.37 |
-3.36 |
|
VLPPLPFPL |
8.66
|
-7.05 |
-4.04 |
|
FDRPPPLTP |
8.73
|
-6.22 |
-3.21 |
| P16892 |
YHDPNDEPE |
10.01
|
-3.97 |
-0.96 |
|
NDEPEGEPI |
10.50
|
-3.51 |
-0.50 |
|
EGEPIPPSF |
11.77
|
-3.27 |
-0.26 |
| P40210 |
PTEPQTNDS |
14.36
|
-2.15 |
0.86 |
|
EVDPTEPQT |
14.46
|
-1.91 |
1.10 |
| Q12114 |
KSEPVGTPN |
9.08
|
-2.94 |
0.07 |
|
HETAPVSPV |
12.31
|
-4.64 |
-1.63 |
| P21268 |
NLSKPISPP |
9.70
|
-4.24 |
-1.23 |
|
LSKPISPPP |
9.82
|
-4.91 |
-1.90 |
|
PISPPPSLK |
11.17
|
-4.15 |
-1.14 |
| Q12753 |
MIKPKGRPS |
7.33
|
-5.49 |
-2.48 |
|
MMIKPKGRP |
8.61
|
-6.87 |
-3.86 |
|
NDLPDTSPM |
8.88
|
-4.05 |
-1.04 |
| P14681 |
YHDPSDEPE |
11.40
|
-3.91 |
-0.90 |
|
SDEPEYPPL |
11.61
|
-1.79 |
1.22 |
|
PEYPPLNLD |
12.43
|
-3.62 |
-0.61 |
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