ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-25.PDB
Scoring matrix: FUS1_1OV32-25_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 12.88
Foldx random average score for Saccharomyces cerevisiae: 12.008

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1255259
Proteins after disorder filtering: 4253
 Total fragments: 63935
Proteins after pattern filtering: 2151
 Total fragments: 13975
Proteins after MINT filtering: 23
 Total fragments: 207


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

12.88

2.02

0.00

Best peptides

HMKRFRRAP

0.00

0.34

-1.68

         
Interactors      
P36119

TRPTVQPSN

9.81

-1.56

-3.58

RPTVQPSNQ

10.33

-1.11

-3.13

STTRPTVQP

11.87

1.13

-0.89

P53950

PNPSIPSAS

7.54

-0.27

-2.29

TKTAPSTAP

9.33

-0.33

-2.35

PPAPLLPLP

9.82

-2.39

-4.41

P40073

YPQQQPSHT

10.79

-0.12

-2.14

P24583

ANAPLPPQP

8.61

-0.63

-2.65

PLPPQPRKH

9.28

-2.42

-4.44

PPQPRKHDK

9.85

-0.04

-2.06

P53947

PFNPIQDPF

9.35

-2.53

-4.55

P34250

YHSKKPSNP

6.42

-1.38

-3.40

LYPKEPPAR

8.15

-0.39

-2.41

SNPDLPTAL

8.48

-1.49

-3.51

P53046

TPPTPKSAG

10.66

0.55

-1.47

Q12280

VTPPLRPQS

7.76

-2.52

-4.54

GSPSKPGNN

8.94

-1.17

-3.19

TPPLRPQSS

10.28

-0.37

-2.39

P39732

RHPSIAPPS

7.14

-0.56

-2.58

STRHPSIAP

8.20

-0.15

-2.17

RSPSVSPVR

11.07

0.30

-1.72

P40091

QNPSHPHHN

9.95

-0.27

-2.29

PVTWDPSSP

11.25

2.00

-0.02

NPSHPHHNS

11.87

0.72

-1.30

P40450

SPKLFPRLS

6.59

-3.25

-5.27

KLPQLPPPP

8.32

-3.53

-5.55

APPPLPDLF

8.62

-3.84

-5.86

P25376

DRPSSQPHL

10.85

-2.51

-4.53

P41832

PAPPMMPAS

7.22

-1.26

-3.28

TDGVIPPAP

7.69

-1.07

-3.09

PPPPPVPAK

8.70

0.49

-1.53

Q03466

SGSSVPMAP

9.88

1.22

-0.80

PMAPDTFNV

9.97

0.23

-1.79

SSVPMAPDT

11.10

-0.34

-2.36

P31374

FRKTKPPPP

5.42

-3.87

-5.89

PERPSFRQP

8.36

0.09

-1.93

QPRLPSTAS

9.90

0.77

-1.25

P32917

NIPPKVAPF

8.37

-0.58

-2.60

DNIPPKVAP

8.54

0.72

-1.30

YLPQHPHRT

9.30

-1.51

-3.53

P40020

KSRVLPPLP

7.76

-4.93

-6.95

LPPYLSPQN

9.53

-1.74

-3.76

RPPPLTPEK

9.63

-0.91

-2.93

P16892

EGEPIPPSF

10.56

-1.00

-3.02

EPEGEPIPP

11.12

0.77

-1.25

P40210

HDEVDPTEP

11.41

-0.64

-2.66

Q12114

GHETAPVSP

11.09

2.39

0.37

SEPVGTPNI

11.82

1.31

-0.71

P21268

LSKPISPPP

7.77

-1.35

-3.37

SKPISPPPS

10.18

-0.03

-2.05

LNLSKPISP

11.13

1.70

-0.32

Q12753

NHRYPPMAP

5.47

-1.15

-3.17

MIKPKGRPS

7.77

-1.59

-3.61

MMIKPKGRP

8.00

-2.57

-4.59

P14681

DEPEYPPLN

9.94

-2.55

-4.57

EPEYPPLNL

11.26

-1.07

-3.09

 


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