ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-21.PDB
Scoring matrix: FUS1_1OV32-21_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.61
Foldx random average score for Saccharomyces cerevisiae: 17.356

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1876891
Proteins after disorder filtering: 4448
 Total fragments: 74856
Proteins after pattern filtering: 1701
 Total fragments: 4420
Proteins after MINT filtering: 21
 Total fragments: 61


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

19.61

-1.51

0.00

Best peptides

ERRWGRPNME

0.00

-3.36

-1.85

         
Interactors      
Q12280

PLRPQSSSKI

10.79

-5.18

-3.67

PSKPGNNNSY

13.53

-2.52

-1.01

VTPPLRPQSS

17.02

-2.84

-1.33

P31374

NISPERPSFR

11.96

-5.28

-3.77

PGTPVFPNLD

12.91

-4.16

-2.65

PPSPDQENHI

13.57

-3.60

-2.09

P36119

RPTVQPSNQS

13.99

-3.13

-1.62

TRPTVQPSNQ

14.69

-3.18

-1.67

P40073

GYPQQQPSHT

13.47

-3.99

-2.48

P24583

PPQPRKHDKT

14.96

-3.99

-2.48

PLPPQPRKHD

17.28

-5.54

-4.03

P39732

HPSIAPPSKL

11.33

-4.73

-3.22

RSPSVSPVRT

15.03

-4.46

-2.95

P40091

TWDPSSPSSV

13.88

-3.01

-1.50

SQNPSHPHHN

14.47

-3.44

-1.93

SPASSPVTWD

16.17

-2.58

-1.07

P40450

PPLPESLSMN

14.53

-5.06

-3.55

PPPPLPQSLL

14.98

-6.23

-4.72

SSPKLFPRLS

15.28

-6.08

-4.57

P32917

DYLPQHPHRT

10.62

-4.98

-3.47

PQHPHRTSSL

15.54

-4.27

-2.76

P25376

DRPSSQPHLG

13.30

-4.78

-3.27

P40020

PPYLSPQNKD

11.38

-6.08

-4.57

SEEPTSPTRQ

11.57

-5.81

-4.30

MSLPVTPVKS

14.53

-5.02

-3.51

P41832

PPLPSVLSSS

16.90

-2.61

-1.10

PPPPLPSVLS

17.20

-6.45

-4.94

Q12114

SEPVGTPNIE

11.13

-4.85

-3.34

Q03466

PMAPDTFNVK

11.49

-4.20

-2.69

SVPMAPDTFN

13.52

-6.45

-4.94

P14681

EPEYPPLNLD

17.21

-5.00

-3.49

P53046

PPTPKSAGHT

16.29

-5.09

-3.58

P53947

FNPIQDPFTD

14.72

-4.30

-2.79

Q12753

IKPKGRPSTT

11.37

-3.93

-2.42

PRMPKTGSRQ

12.20

-4.01

-2.50

YPPMAPTTVA

13.65

-6.24

-4.73

P34250

LYPKEPPARK

13.78

-5.72

-4.21

SSNPDLPTAL

14.39

-4.44

-2.93

P53950

PSIPSASTST

14.26

-3.16

-1.65

APNPSIPSAS

15.93

-3.36

-1.85

P40210

EVDPTEPQTN

15.90

-4.53

-3.02

 


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