ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-15.PDB
Scoring matrix: FUS1_1OV32-15_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.27
Foldx random average score for Saccharomyces cerevisiae: 10.788

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1422009
Proteins after disorder filtering: 3958
 Total fragments: 35075
Proteins after pattern filtering: 1527
 Total fragments: 4227
Proteins after MINT filtering: 15
 Total fragments: 44


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.27

-0.62

0.00

Best peptides

RFWFIVKIR

0.00

-5.14

-4.52

         
Interactors      
P31374

RKTKPPPPL

9.15

-5.83

-5.21

FPNLDPTHS

9.68

-4.92

-4.30

ISPERPSFR

10.19

-2.02

-1.40

P53950

NPSIPSAST

9.02

-4.27

-3.65

APLLPLPSL

10.44

-4.29

-3.67

NPNGAPLRR

10.70

-2.99

-2.37

P36119

RPTVQPSNQ

6.89

-4.71

-4.09

P40073

YPQQQPSHT

9.74

-2.63

-2.01

P24583

LPPQPRKHD

10.24

-1.43

-0.81

NAPLPPQPR

10.48

-4.56

-3.94

P39732

HPSIAPPSK

8.40

-3.92

-3.30

SPSVSPVRT

9.62

-2.65

-2.03

RSPSVSPVR

9.71

-2.60

-1.98

P53947

FNPIQDPFT

7.30

-3.54

-2.92

ASPFNPIQD

10.64

-1.53

-0.91

P40450

APPLPNGLL

9.40

-4.64

-4.02

PKLFPRLSS

10.48

-3.85

-3.23

P32917

YLPQHPHRT

9.08

-2.86

-2.24

FPPYSPLLP

9.13

-3.36

-2.74

RFPPYSPLL

9.42

-4.20

-3.58

P25376

RPSSQPHLG

10.07

-1.56

-0.94

P40020

LPPLPFPLY

8.16

-5.17

-4.55

APSIPVEHS

8.80

-4.02

-3.40

LPPYLSPQN

8.95

-2.23

-1.61

P34250

LYPKEPPAR

6.88

-4.14

-3.52

KPAYVPPED

9.53

-2.92

-2.30

P14681

EPEYPPLNL

10.60

-3.86

-3.24

Q12753

YPPMAPTTV

7.58

-2.69

-2.07

IKPKGRPST

8.65

-2.94

-2.32

INSPRMPKT

9.31

-1.04

-0.42

Q03466

SVPMAPDTF

10.66

-3.35

-2.73

 


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