ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-14.PDB
Scoring matrix: FUS1_1OV32-14_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.12
Foldx random average score for Saccharomyces cerevisiae: 12.966

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1356575
Proteins after disorder filtering: 4119
 Total fragments: 41320
Proteins after pattern filtering: 1623
 Total fragments: 4552
Proteins after MINT filtering: 19
 Total fragments: 58


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.12

-2.15

0.00

Best peptides

RRFIIWKNW

0.00

-4.69

-2.54

         
Interactors      
Q12280

VTPPLRPQS

12.33

-1.64

0.51

P31374

RKTKPPPPL

9.53

-6.16

-4.01

KPGTPVFPN

10.51

-3.86

-1.71

NISPERPSF

11.10

-1.43

0.72

P36119

RPTVQPSNQ

7.49

-6.87

-4.72

TRPTVQPSN

12.01

-2.61

-0.46

P40073

GYPQQQPSH

12.04

-3.09

-0.94

P24583

LPPQPRKHD

10.96

-2.17

-0.02

NAPLPPQPR

12.64

-3.73

-1.58

P39732

HPSIAPPSK

10.58

-4.89

-2.74

RHPSIAPPS

12.44

-3.66

-1.51

P21268

KPISPPPSL

10.96

-2.35

-0.20

SKPISPPPS

12.67

-4.67

-2.52

P40091

NPSHPHHNS

10.57

-3.28

-1.13

P40450

APPLPNGLL

9.01

-5.65

-3.50

SSPKLFPRL

10.19

-2.65

-0.50

PPPLPQSLL

10.42

-3.79

-1.64

P32917

RFPPYSPLL

10.15

-4.28

-2.13

IPPKVAPFG

11.03

-1.94

0.21

NIPPKVAPF

11.56

-3.42

-1.27

P25376

RPSSQPHLG

10.67

-3.14

-0.99

DRPSSQPHL

11.94

-2.02

0.13

P40020

LPPLPFPLY

9.57

-4.77

-2.62

APSIPVEHS

9.59

-5.57

-3.42

VNPHSIPFS

11.00

-4.69

-2.54

P41832

PPPPVPAKL

12.80

-3.21

-1.06

PPPPPMALF

12.84

-4.54

-2.39

P53947

ASPFNPIQD

11.91

-2.93

-0.78

P34250

KPAYVPPED

10.72

-2.97

-0.82

LYPKEPPAR

10.72

-3.36

-1.21

KPSNPPSSG

11.90

-2.91

-0.76

P14681

EPEYPPLNL

10.02

-4.85

-2.70

Q12753

IKPKGRPST

11.98

-1.44

0.71

Q03466

SVPMAPDTF

10.97

-4.75

-2.60

P53950

APNPSIPSA

12.55

-2.12

0.03

NPNGAPLRR

12.63

-2.59

-0.44

 


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