ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-13.PDB
Scoring matrix: FUS1_1OV32-13_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.57
Foldx random average score for Saccharomyces cerevisiae: 12.614

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7177
 Total fragments: 1614017
Proteins after disorder filtering: 4667
 Total fragments: 93822
Proteins after pattern filtering: 2221
 Total fragments: 13714
Proteins after MINT filtering: 23
 Total fragments: 218


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.57

0.46

0.00

Best peptides

HRRIYFLR

0.00

-3.97

-4.42

         
Interactors      
P36119

RPTVQPSN

9.42

-4.12

-4.58

PTVQPSNQ

10.37

-2.24

-2.70

P53950

PAPLLPLP

8.56

-5.91

-6.37

TPPAPLLP

8.77

-3.00

-3.46

NPSIPSAS

9.56

-4.29

-4.75

P40073

YPQQQPSH

10.36

-3.01

-3.46

GYPQQQPS

12.61

-1.58

-2.04

P24583

LPPQPRKH

9.62

-2.44

-2.90

NAPLPPQP

9.77

-3.25

-3.71

APLPPQPR

10.73

-2.98

-3.44

P53947

FNPIQDPF

8.94

-4.61

-5.07

SPFNPIQD

10.63

-1.50

-1.96

PIQDPFTD

11.73

-2.42

-2.88

P34250

YPKEPPAR

7.52

-4.69

-5.15

KKPSNPPS

9.32

-2.49

-2.95

KPSNPPSS

9.44

-3.80

-4.25

P53046

QLSTPPTP

10.37

-4.13

-4.59

LSTPPTPK

10.76

-2.14

-2.60

TPPTPKSA

11.77

-1.94

-2.40

Q12280

TPPLRPQS

9.37

-3.52

-3.98

INTAPASP

11.79

-2.03

-2.48

APASPEEP

11.97

-1.94

-2.40

P39732

HPSIAPPS

8.68

-5.81

-6.26

SPSVSPVR

8.73

-4.37

-4.83

RHPSIAPP

9.59

-5.05

-5.50

P40091

PSHPHHNS

11.15

1.23

0.77

SPASSPVT

11.50

-2.41

-2.87

PASSPVTW

12.20

-1.51

-1.97

P40450

PKLFPRLS

6.69

-4.89

-5.34

PPPLPDLF

7.31

-4.23

-4.69

APAPPPLP

8.33

-4.48

-4.94

P25376

PSSQPHLG

10.25

-3.41

-3.87

DRPSSQPH

12.49

-1.87

-2.33

P41832

PPPLPSVL

8.15

-5.75

-6.21

TPPPPPLP

8.17

-3.38

-3.84

PPPPPPVP

9.24

-4.68

-5.13

Q03466

VPMAPDTF

11.57

-2.23

-2.69

GSSVPMAP

12.07

-2.05

-2.50

P31374

DFEQPRLP

7.61

-4.71

-5.17

PDDLPPLK

7.86

-4.69

-5.15

TKPPPPLD

8.03

-3.75

-4.21

P32917

FPPYSPLL

6.70

-3.25

-3.71

RFPPYSPL

8.05

-5.85

-6.30

PPYSPLLP

8.80

-4.02

-4.47

P40020

SRVLPPLP

5.60

-6.83

-7.29

LPPLPFPL

8.00

-3.97

-4.42

TPESPLNR

8.39

-2.52

-2.98

P16892

GEPIPPSF

10.11

-2.98

-3.44

YHDPNDEP

10.11

-2.54

-3.00

P40210

DPTEPQTN

11.82

-2.11

-2.56

PTEPQTND

12.53

-0.37

-0.82

Q12114

HETAPVSP

10.57

-3.91

-4.37

EPVGTPNI

11.72

-1.64

-2.09

P21268

SKPISPPP

9.51

-3.52

-3.98

KPISPPPS

9.76

-1.66

-2.11

PISPPPSL

11.57

-2.30

-2.75

Q12753

HRYPPMAP

7.65

-6.25

-6.71

IPQSPPLS

8.16

-2.81

-3.27

NFSIPQSP

9.17

-3.81

-4.26

P14681

EPEYPPLN

7.51

-4.31

-4.76

PEYPPLNL

10.61

-1.59

-2.04

YHDPSDEP

11.34

-1.70

-2.15

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER