ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-12.PDB
Scoring matrix: FUS1_1OV32-12_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.65
Foldx random average score for Saccharomyces cerevisiae: 9.236

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1264115
Proteins after disorder filtering: 4522
 Total fragments: 71682
Proteins after pattern filtering: 2215
 Total fragments: 13281
Proteins after MINT filtering: 23
 Total fragments: 185


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.65

-2.00

0.00

Best peptides

RFIPEWWR

0.00

-4.36

-2.36

         
Interactors      
P36119

TTRPTVQP

7.28

-4.14

-2.14

PTVQPSNQ

8.28

-3.55

-1.55

P53950

PSIPSAST

7.02

-4.12

-2.12

APNPSIPS

7.42

-3.62

-1.62

NTPPAPLL

7.61

-4.04

-2.04

P40073

DGYPQQQP

8.02

-3.80

-1.80

GYPQQQPS

9.20

-2.43

-0.43

P24583

PLPPQPRK

6.58

-4.94

-2.94

NAPLPPQP

7.65

-3.64

-1.64

LPPQPRKH

7.92

-4.04

-2.04

P53947

SPFNPIQD

6.34

-5.07

-3.07

NPIQDPFT

6.72

-4.65

-2.65

ASPFNPIQ

8.20

-3.20

-1.20

P34250

LYPKEPPA

6.70

-4.25

-2.25

ALYPKEPP

7.09

-4.45

-2.45

SSNPDLPT

7.30

-4.66

-2.66

P53046

STPPTPKS

6.87

-4.68

-2.68

LSTPPTPK

9.11

-3.99

-1.99

Q12280

VTPPLRPQ

6.14

-3.63

-1.63

ASPEEPKE

7.14

-4.00

-2.00

PSKPGNNN

7.93

-3.80

-1.80

P39732

PSIAPPSK

6.12

-5.10

-3.10

PSVSPVRT

6.52

-5.13

-3.13

TRHPSIAP

6.86

-3.86

-1.86

P40091

PSHPHHNS

6.88

-4.51

-2.51

SQNPSHPH

7.42

-3.52

-1.52

QNPSHPHH

8.69

-3.71

-1.71

P40450

GAVPPPPP

5.53

-5.51

-3.51

SSPKLFPR

5.89

-4.23

-2.23

AVPPPPPP

6.26

-4.97

-2.97

P25376

NDRPSSQP

8.80

-2.29

-0.29

DRPSSQPH

8.83

-3.09

-1.09

P41832

GVIPPAPP

5.52

-4.77

-2.77

PAPPMMPA

6.28

-4.84

-2.84

ETPPPPPL

6.38

-4.86

-2.86

Q03466

SSVPMAPD

7.20

-4.15

-2.15

SVPMAPDT

9.20

-3.18

-1.18

P31374

PERPSFRQ

5.31

-5.75

-3.75

NNISPERP

5.92

-5.55

-3.55

TKPPPPLD

7.28

-4.44

-2.44

P32917

SRFPPYSP

5.56

-5.82

-3.82

YSPLLPPF

7.24

-4.08

-2.08

DYLPQHPH

7.79

-5.61

-3.61

P40020

PSIPVEHS

6.32

-4.82

-2.82

SRVLPPLP

6.89

-5.47

-3.47

TSAPSIPV

6.98

-3.93

-1.93

P16892

HDPNDEPE

7.67

-1.97

0.03

GEPIPPSF

8.43

-3.34

-1.34

EGEPIPPS

9.03

-3.30

-1.30

P40210

VDPTEPQT

8.29

-3.85

-1.85

EVDPTEPQ

9.21

-1.75

0.25

Q12114

EPVGTPNI

8.24

-4.85

-2.85

P21268

KPISPPPS

6.28

-5.66

-3.66

SKPISPPP

7.46

-4.01

-2.01

Q12753

HRYPPMAP

5.46

-6.15

-4.15

FSIPQSPP

6.04

-4.26

-2.26

IKPKGRPS

6.99

-3.95

-1.95

P14681

PEYPPLNL

6.85

-6.06

-4.06

SDEPEYPP

7.63

-3.33

-1.33

HDPSDEPE

8.41

-2.03

-0.03

 


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