ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-9.PDB
Scoring matrix: FUS1_1FYN-9_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.16
Foldx random average score for Saccharomyces cerevisiae: 12.147

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1591559
Proteins after disorder filtering: 4766
 Total fragments: 87186
Proteins after pattern filtering: 2204
 Total fragments: 11981
Proteins after MINT filtering: 21
 Total fragments: 193


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

13.16

1.61

0.00

Best peptides

RRPIPPCW

0.00

-2.96

-4.57

         
Interactors      
Q12280

PPLRPQSS

10.04

-3.20

-4.81

APASPEEP

10.35

-2.37

-3.98

NVTPPLRP

10.75

-3.41

-5.02

P36119

RPTVQPSN

6.71

-1.83

-3.44

TRPTVQPS

11.35

-1.77

-3.38

P53046

TPPTPKSA

9.78

-0.87

-2.48

QLSTPPTP

11.53

-2.44

-4.05

LSTPPTPK

11.83

-1.94

-3.55

P24583

RANAPLPP

8.31

-2.37

-3.98

NAPLPPQP

9.82

-5.17

-6.78

APLPPQPR

11.88

-2.66

-4.27

P39732

RHPSIAPP

6.74

-2.84

-4.45

RSPSVSPV

7.58

-0.90

-2.51

HPSIAPPS

10.16

-3.25

-4.86

P21268

NLSKPISP

8.31

-1.38

-2.99

SKPISPPP

8.47

-4.13

-5.74

KPISPPPS

10.53

-2.38

-3.99

P40091

WDPSSPSS

9.83

0.64

-0.97

MSSPASSP

9.85

-1.14

-2.75

VTWDPSSP

10.26

-2.12

-3.73

P40450

APPLPNGL

7.92

-3.93

-5.54

PPPLPESL

8.51

-4.01

-5.62

DLVTPPAP

8.81

-3.66

-5.27

P32917

FPPYSPLL

8.79

-2.61

-4.22

SRFPPYSP

8.97

-2.50

-4.11

RFPPYSPL

9.11

-0.37

-1.98

P25376

RPSSQPHL

10.17

-0.63

-2.24

DRPSSQPH

11.52

-1.87

-3.48

P40020

RVLPPLPF

7.35

-2.50

-4.11

PHSIPFSV

8.04

-3.71

-5.32

APSIPVEH

8.16

-4.52

-6.13

P41832

APPMMPAS

7.10

-3.63

-5.24

DGVIPPAP

8.27

-3.00

-4.61

APPPPPPP

10.25

-3.63

-5.24

P16892

GEPIPPSF

8.05

-3.72

-5.33

Q03466

GSSVPMAP

9.31

-2.79

-4.40

SVPMAPDT

10.16

-2.83

-4.44

Q12114

HETAPVSP

10.47

-1.16

-2.77

P31374

RKTKPPPP

4.52

-4.33

-5.94

KPGTPVFP

8.45

-3.49

-5.10

KPPPPLDF

8.46

-2.13

-3.74

P53947

FNPIQDPF

9.63

-3.57

-5.18

ASPFNPIQ

10.43

-1.92

-3.53

SPFNPIQD

12.12

-3.71

-5.32

Q12753

NFSIPQSP

7.13

-3.64

-5.25

HRYPPMAP

7.82

-2.85

-4.46

RYPPMAPT

8.20

-1.02

-2.63

P34250

KPSNPPSS

8.44

-2.55

-4.16

NPDLPTAL

8.89

-4.04

-5.65

KPAYVPPE

9.47

-2.40

-4.01

P14681

EPEYPPLN

9.55

-3.90

-5.51

P53950

NPSIPSAS

7.37

-3.84

-5.45

APLLPLPS

9.62

-4.44

-6.05

GSNTPPAP

9.64

-2.87

-4.48

 


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