ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-8.PDB
Scoring matrix: FUS1_1FYN-8_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.63
Foldx random average score for Saccharomyces cerevisiae: 9.456

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1336411
Proteins after disorder filtering: 4372
 Total fragments: 67572
Proteins after pattern filtering: 2174
 Total fragments: 12957
Proteins after MINT filtering: 23
 Total fragments: 199


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.63

0.58

0.00

Best peptides

KRFRKPPF

0.00

-0.80

-1.38

         
Interactors      
P36119

TRPTVQPS

7.63

-1.04

-1.62

TTRPTVQP

9.21

-1.78

-2.36

P53950

PLLPLPSL

6.46

-4.56

-5.14

PAPLLPLP

6.83

-3.37

-3.95

PPAPLLPL

7.11

-2.30

-2.88

P40073

YPQQQPSH

8.36

-2.17

-2.75

DGYPQQQP

9.32

-1.24

-1.82

P24583

PLPPQPRK

6.46

-4.14

-4.72

ANAPLPPQ

7.00

-3.26

-3.84

APLPPQPR

8.66

-1.46

-2.04

P53947

FNPIQDPF

7.95

-0.34

-0.92

PFNPIQDP

8.50

-1.54

-2.12

ASPFNPIQ

9.08

-1.54

-2.12

P34250

SKKPSNPP

6.47

-2.01

-2.59

PKPAYVPP

6.57

-1.49

-2.07

LYPKEPPA

6.83

-1.81

-2.39

P53046

PPTPKSAG

9.45

-0.32

-0.90

Q12280

GSPSKPGN

7.37

-1.97

-2.55

VTPPLRPQ

7.54

-3.51

-4.09

TPPLRPQS

8.48

-2.12

-2.70

P39732

TRHPSIAP

4.93

-1.92

-2.50

SRSPSVSP

5.79

-1.26

-1.84

RHPSIAPP

7.36

-2.68

-3.26

P40091

QNPSHPHH

8.40

-1.60

-2.18

WDPSSPSS

9.06

-0.90

-1.48

SQNPSHPH

9.14

0.22

-0.36

P40450

APPPLPDL

5.22

-4.24

-4.82

KLPQLPPP

5.92

-4.49

-5.07

SSPKLFPR

5.92

-4.06

-4.64

P25376

DRPSSQPH

5.99

-2.68

-3.26

RPSSQPHL

7.70

-2.98

-3.56

NDRPSSQP

8.99

-1.84

-2.42

P41832

PPPPMALF

6.19

-3.29

-3.87

PPPPPPPM

6.21

-3.34

-3.92

PPPPVPAK

6.42

-3.51

-4.09

Q03466

VPMAPDTF

9.07

-1.01

-1.59

P31374

KKPGTPVF

6.36

-2.82

-3.40

EQPRLPST

6.76

-4.03

-4.61

TPDDLPPL

6.90

-2.34

-2.92

P32917

YSPLLPPF

5.03

-4.35

-4.93

SRFPPYSP

5.83

-1.64

-2.22

FPPYSPLL

5.87

-2.35

-2.93

P40020

VNPHSIPF

5.97

-1.66

-2.24

VLPPLPFP

6.05

-4.28

-4.86

PPLPFPLY

6.19

-3.26

-3.84

P16892

GEPIPPSF

7.45

-2.04

-2.62

EGEPIPPS

8.61

-1.54

-2.12

EPEGEPIP

8.68

-1.54

-2.12

P40210

VDPTEPQT

9.41

-1.41

-1.99

Q12114

EPVGTPNI

9.01

-1.42

-2.00

P21268

SKPISPPP

5.81

-2.34

-2.92

LSKPISPP

7.23

-3.05

-3.63

KPISPPPS

8.75

-1.45

-2.03

Q12753

PRMPKTGS

4.70

-2.14

-2.72

HRYPPMAP

6.34

-2.67

-3.25

NSPRMPKT

6.86

-4.10

-4.68

P14681

DEPEYPPL

7.22

-1.75

-2.33

DPSDEPEY

7.73

-1.58

-2.16

 


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