ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-7.PDB
Scoring matrix: FUS1_1FYN-7_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.91
Foldx random average score for Saccharomyces cerevisiae: 9.703

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1337945
Proteins after disorder filtering: 4523
 Total fragments: 57019
Proteins after pattern filtering: 1961
 Total fragments: 8783
Proteins after MINT filtering: 19
 Total fragments: 116


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.91

-2.53

0.00

Best peptides

WKRRIPRR

0.00

-2.34

0.19

         
Interactors      
Q12280

NVTPPLRP

9.23

-3.26

-0.73

VTPPLRPQ

9.51

-1.72

0.81

P31374

RKTKPPPP

6.03

-4.29

-1.76

TKPPPPLD

6.38

-3.77

-1.24

KKPGTPVF

7.18

-2.96

-0.43

P36119

RPTVQPSN

9.54

-1.56

0.97

P24583

LPPQPRKH

8.76

-5.14

-2.61

APLPPQPR

8.97

-4.09

-1.56

PLPPQPRK

9.05

-2.51

0.02

P39732

HPSIAPPS

7.61

-3.30

-0.77

RSPSVSPV

8.91

-1.41

1.12

RHPSIAPP

9.13

-2.17

0.36

P21268

SKPISPPP

8.51

-4.49

-1.96

LSKPISPP

8.72

-2.51

0.02

KPISPPPS

8.88

-3.34

-0.81

P40091

NPSHPHHN

8.85

-3.67

-1.14

QNPSHPHH

9.00

-1.61

0.92

WDPSSPSS

9.17

-0.48

2.05

P40450

PKLFPRLS

6.01

-4.65

-2.12

APAPPPLP

8.33

-4.88

-2.35

LPPPPPPP

8.38

-4.21

-1.68

P32917

IPPKVAPF

6.81

-3.25

-0.72

FPPYSPLL

6.99

-2.86

-0.33

LPQHPHRT

7.21

-4.81

-2.28

P25376

PSSQPHLG

9.25

-3.54

-1.01

RPSSQPHL

9.36

-1.63

0.90

P40020

LPPLPFPL

7.75

-4.97

-2.44

MSLPVTPV

8.04

-2.90

-0.37

APSIPVEH

8.18

-4.64

-2.11

P41832

IPPAPPMM

6.20

-5.38

-2.85

PPPPPPMA

7.89

-4.31

-1.78

APPMMPAS

8.62

-3.28

-0.75

P16892

GEPIPPSF

8.21

-4.17

-1.64

EGEPIPPS

9.36

-2.51

0.02

P53947

ASPFNPIQ

5.90

-3.07

-0.54

FNPIQDPF

8.72

-3.20

-0.67

P34250

KKPSNPPS

6.09

-2.68

-0.15

PKEPPARK

6.34

-4.20

-1.67

KPAYVPPE

7.67

-3.09

-0.56

P14681

EPEYPPLN

7.50

-4.10

-1.57

Q12753

IKPKGRPS

6.61

-2.87

-0.34

HRYPPMAP

7.76

-3.35

-0.82

IPQSPPLS

7.79

-4.06

-1.53

P53046

LSTPPTPK

8.14

-3.25

-0.72

P53950

NTPPAPLL

9.03

-2.67

-0.14

NPSIPSAS

9.03

-3.99

-1.46

PNGAPLRR

9.21

-3.88

-1.35

 


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