ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-29.PDB
Scoring matrix: FUS1_1FYN-29_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.08
Foldx random average score for Saccharomyces cerevisiae: 12.568

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1286785
Proteins after disorder filtering: 3915
 Total fragments: 39930
Proteins after pattern filtering: 2000
 Total fragments: 10125
Proteins after MINT filtering: 22
 Total fragments: 158


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.08

-1.65

0.00

Best peptides

KFRPWMPMRF

0.00

-3.98

-2.33

         
Interactors      
P36119

RPTVQPSNQS

12.29

-2.74

-1.09

TRPTVQPSNQ

12.43

-3.98

-2.33

P53950

VVAPNPSIPS

10.05

-6.15

-4.50

NPNGAPLRRY

11.02

-9.81

-8.16

NTPPAPLLPL

11.32

-5.83

-4.18

P40073

QFDGYPQQQP

12.42

-3.20

-1.55

P24583

PLPPQPRKHD

10.46

-5.15

-3.50

AERANAPLPP

10.94

-3.96

-2.31

NAPLPPQPRK

11.80

-4.09

-2.44

P53947

PFNPIQDPFT

7.81

-5.83

-4.18

P34250

LYPKEPPARK

10.00

-7.16

-5.51

EPKPAYVPPE

10.60

-2.39

-0.74

KPAYVPPEDV

10.68

-4.36

-2.71

P53046

NQLSTPPTPK

11.82

-5.78

-4.13

QLSTPPTPKS

12.31

-3.36

-1.71

Q12280

GTNVTPPLRP

10.54

-4.63

-2.98

TAPASPEEPK

10.55

-4.75

-3.10

PLRPQSSSKI

11.34

-2.31

-0.66

P39732

RSPSVSPVRT

10.73

-4.71

-3.06

TRHPSIAPPS

10.90

-4.21

-2.56

RHPSIAPPSK

12.19

-3.98

-2.33

P40091

SQNPSHPHHN

11.65

-4.14

-2.49

P40450

KLPQLPPPPP

9.37

-8.35

-6.70

APPPLPDLFK

9.67

-6.36

-4.71

SPKLFPRLSS

10.01

-5.74

-4.09

P25376

DRPSSQPHLG

11.18

-6.99

-5.34

NDRPSSQPHL

12.52

-1.43

0.22

P41832

VIPPAPPMMP

8.40

-7.03

-5.38

PPPPLPSVLS

10.12

-6.27

-4.62

IPPAPPMMPA

10.77

-5.28

-3.63

Q03466

SVPMAPDTFN

12.05

-3.16

-1.51

P31374

SFRKTKPPPP

7.62

-6.45

-4.80

FRKTKPPPPL

8.19

-6.17

-4.52

KKPGTPVFPN

9.70

-5.60

-3.95

P32917

RFPPYSPLLP

8.39

-4.55

-2.90

DYLPQHPHRT

9.05

-7.96

-6.31

SRFPPYSPLL

9.56

-4.61

-2.96

P40020

KSRVLPPLPF

7.97

-8.69

-7.04

VLPPLPFPLY

8.70

-7.14

-5.49

SAPSIPVEHS

8.86

-6.02

-4.37

P16892

TYHDPNDEPE

11.03

-3.10

-1.45

P40210

HDEVDPTEPQ

12.08

-3.73

-2.08

P21268

LSKPISPPPS

10.36

-4.11

-2.46

PISPPPSLKK

11.03

-6.16

-4.51

PLNLSKPISP

11.26

-3.71

-2.06

Q12753

DLPDTSPMSS

9.80

-5.87

-4.22

SINSPRMPKT

10.38

-3.81

-2.16

HRYPPMAPTT

10.53

-4.94

-3.29

P14681

DEPEYPPLNL

10.93

-4.78

-3.13

EPEYPPLNLD

12.26

-3.45

-1.80

 


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