ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-27.PDB
Scoring matrix: FUS1_1FYN-27_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 17.72
Foldx random average score for Saccharomyces cerevisiae: 16.478

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1444084
Proteins after disorder filtering: 4614
 Total fragments: 87660
Proteins after pattern filtering: 2304
 Total fragments: 18197
Proteins after MINT filtering: 23
 Total fragments: 273


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

17.72

-2.56

0.00

Best peptides

MDRRMHIRR

0.00

-2.99

-0.43

         
Interactors      
P36119

TTRPTVQPS

10.37

-3.86

-1.30

RPTVQPSNQ

13.79

-5.17

-2.61

STTRPTVQP

13.89

-3.22

-0.66

P53950

VVAPNPSIP

10.68

-3.11

-0.55

VAPNPSIPS

12.60

-4.76

-2.20

GSNTPPAPL

12.86

-3.27

-0.71

P40073

DGYPQQQPS

15.30

-3.12

-0.56

YPQQQPSHT

15.50

-4.23

-1.67

FDGYPQQQP

15.94

-5.19

-2.63

P24583

PPQPRKHDK

10.59

-3.74

-1.18

APLPPQPRK

10.60

-7.02

-4.46

PLPPQPRKH

11.47

-4.50

-1.94

P53947

ASPFNPIQD

13.82

-4.20

-1.64

PFNPIQDPF

15.17

-2.70

-0.14

P34250

PKEPPARKS

11.50

-4.33

-1.77

PSNPPSSGN

12.00

-2.48

0.08

YPKEPPARK

12.83

-8.24

-5.68

P53046

TPPTPKSAG

12.21

-1.68

0.88

PPTPKSAGH

12.81

-2.82

-0.26

STPPTPKSA

13.50

-3.40

-0.84

Q12280

PPLRPQSSS

10.78

-4.02

-1.46

PLRPQSSSK

11.44

-2.10

0.46

TNVTPPLRP

11.74

-6.97

-4.41

P39732

TRHPSIAPP

11.78

-3.71

-1.15

SSSPSPSPT

12.47

-2.49

0.07

SPSVSPVRT

12.85

-4.81

-2.25

P40091

MSSPASSPV

8.73

-3.45

-0.89

PSHPHHNSR

10.87

-3.26

-0.70

PSSPSSVGS

14.37

-2.43

0.13

P40450

PPPPPPLPQ

10.35

-5.47

-2.91

PPPPPPLPE

10.43

-5.01

-2.45

APAPPPLPD

10.69

-5.26

-2.70

P25376

NDRPSSQPH

12.81

-4.23

-1.67

SNDRPSSQP

12.98

-3.21

-0.65

PSSQPHLGY

15.15

-3.74

-1.18

P41832

PPAPPMMPA

9.32

-5.36

-2.80

PPPPMALFG

10.21

-4.84

-2.28

PPPPPPMAL

10.22

-5.03

-2.47

Q03466

GSSVPMAPD

11.59

-3.68

-1.12

PMAPDTFNV

12.28

-1.39

1.17

SSVPMAPDT

14.47

-2.99

-0.43

P31374

SPERPSFRQ

8.90

-7.38

-4.82

ISPERPSFR

11.56

-2.55

0.01

TKPPPPLDF

12.04

-4.14

-1.58

P32917

SRFPPYSPL

11.41

-4.01

-1.45

TDYLPQHPH

12.41

-4.91

-2.35

PLLPPFGLS

12.90

-3.28

-0.72

P40020

VLPPLPFPL

9.96

-4.99

-2.43

ISLPPYLSP

10.30

-4.66

-2.10

PLTPEKNLY

10.61

-1.70

0.86

P16892

YHDPNDEPE

13.37

-5.27

-2.71

NDEPEGEPI

13.44

-2.72

-0.16

P40210

VDPTEPQTN

10.58

-1.64

0.92

PTEPQTNDS

14.19

-1.35

1.21

HDEVDPTEP

14.26

-3.73

-1.17

Q12114

KSEPVGTPN

13.45

-3.19

-0.63

GHETAPVSP

15.45

-0.48

2.08

P21268

PISPPPSLK

10.55

-3.59

-1.03

LSKPISPPP

13.63

-4.59

-2.03

SKPISPPPS

16.09

-2.75

-0.19

Q12753

MIKPKGRPS

8.14

-5.29

-2.73

MMIKPKGRP

9.87

-7.86

-5.30

PKGRPSTTC

11.90

-1.44

1.12

P14681

SDEPEYPPL

11.97

-2.09

0.47

YHDPSDEPE

13.73

-4.70

-2.14

PEYPPLNLD

14.17

-3.29

-0.73

 


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