ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-26.PDB
Scoring matrix: FUS1_1FYN-26_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.36
Foldx random average score for Saccharomyces cerevisiae: 13.692

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1299358
Proteins after disorder filtering: 4302
 Total fragments: 62659
Proteins after pattern filtering: 2090
 Total fragments: 12483
Proteins after MINT filtering: 22
 Total fragments: 187


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.36

0.80

0.00

Best peptides

WRFNRRRPF

0.00

-2.01

-2.81

         
Interactors      
P36119

TTRPTVQPS

11.20

-0.83

-1.63

TRPTVQPSN

12.71

-0.73

-1.53

P53950

VAPNPSIPS

12.26

-0.58

-1.38

APNPSIPSA

12.61

-3.41

-4.21

PAPLLPLPS

12.66

-0.67

-1.47

P40073

DGYPQQQPS

11.84

-1.99

-2.79

YPQQQPSHT

13.07

1.05

0.25

GYPQQQPSH

13.44

-1.59

-2.39

P24583

LPPQPRKHD

10.28

0.34

-0.46

APLPPQPRK

11.54

-3.33

-4.13

PLPPQPRKH

11.63

-4.29

-5.09

P53947

SPFNPIQDP

9.99

-3.32

-4.12

FNPIQDPFT

11.73

-0.92

-1.72

PFNPIQDPF

12.73

-1.33

-2.13

P34250

SKKPSNPPS

11.06

-1.44

-2.24

KKPSNPPSS

11.78

-1.47

-2.27

PKEPPARKS

11.89

0.12

-0.68

P53046

LSTPPTPKS

13.08

-1.31

-2.11

NQLSTPPTP

13.58

-2.29

-3.09

Q12280

VTPPLRPQS

9.18

-0.62

-1.42

NVTPPLRPQ

12.24

-2.39

-3.19

PSKPGNNNS

12.69

0.64

-0.16

P39732

PSVSPVRTT

10.05

-1.32

-2.12

TRHPSIAPP

11.52

-2.96

-3.76

RHPSIAPPS

12.44

-2.33

-3.13

P40091

PSHPHHNSR

12.37

-2.88

-3.68

SSPASSPVT

12.85

-0.51

-1.31

QNPSHPHHN

13.23

-0.87

-1.67

P40450

PKLFPRLSS

8.45

-2.90

-3.70

SPKLFPRLS

10.38

-0.36

-1.16

PPLPDLFKT

11.32

-2.74

-3.54

P25376

NDRPSSQPH

12.99

-0.68

-1.48

P41832

PPPPPMALF

11.14

-4.79

-5.59

GVIPPAPPM

11.18

-3.24

-4.04

PPPPPPPPM

11.27

-3.58

-4.38

Q03466

SSVPMAPDT

11.73

-1.15

-1.95

SVPMAPDTF

13.22

-2.00

-2.80

P31374

NISPERPSF

8.19

-2.51

-3.31

PERPSFRQP

8.88

-3.83

-4.63

FEQPRLPST

9.21

-2.98

-3.78

P32917

YLPQHPHRT

10.22

-1.62

-2.42

PQHPHRTSS

10.25

-0.28

-1.08

TDYLPQHPH

10.34

-3.30

-4.10

P40020

SRVLPPLPF

9.89

-3.45

-4.25

LPPLPFPLY

10.12

-2.48

-3.28

VNPHSIPFS

10.44

-1.68

-2.48

P16892

EGEPIPPSF

10.87

-2.13

-2.93

PEGEPIPPS

12.11

-2.52

-3.32

HDPNDEPEG

13.31

-1.76

-2.56

P40210

EVDPTEPQT

13.25

-0.54

-1.34

P21268

SKPISPPPS

11.50

-0.49

-1.29

LSKPISPPP

11.66

-2.85

-3.65

KPISPPPSL

12.58

-2.15

-2.95

Q12753

IKPKGRPST

6.18

-0.74

-1.54

HRYPPMAPT

8.77

-3.54

-4.34

INSPRMPKT

9.21

-3.70

-4.50

P14681

PEYPPLNLD

12.07

-2.79

-3.59

SDEPEYPPL

13.01

-2.21

-3.01

HDPSDEPEY

13.60

-3.90

-4.70

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER