ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-25.PDB
Scoring matrix: FUS1_1FYN-25_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.78
Foldx random average score for Saccharomyces cerevisiae: 13.844

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7177
 Total fragments: 1273007
Proteins after disorder filtering: 4095
 Total fragments: 53242
Proteins after pattern filtering: 2048
 Total fragments: 11937
Proteins after MINT filtering: 20
 Total fragments: 181


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.78

1.31

0.00

Best peptides

RRWRFPPRY

0.00

-6.26

-7.57

         
Interactors      
Q12280

TNVTPPLRP

10.71

-2.04

-3.35

AYSGSPSKP

11.68

0.33

-0.98

VTPPLRPQS

11.89

-1.34

-2.65

P31374

FRKTKPPPP

8.89

-4.48

-5.79

TPDDLPPLK

10.74

-2.89

-4.20

SPERPSFRQ

11.10

-1.65

-2.96

P36119

RPTVQPSNQ

11.37

-2.36

-3.67

TRPTVQPSN

12.24

-0.77

-2.08

P40073

GYPQQQPSH

12.23

0.78

-0.53

P24583

APLPPQPRK

9.17

-2.52

-3.83

PLPPQPRKH

10.10

-2.01

-3.32

ANAPLPPQP

10.94

-0.09

-1.40

P39732

TRHPSIAPP

11.22

0.04

-1.27

SPSVSPVRT

11.90

-2.68

-3.99

SRSPSVSPV

12.15

1.90

0.59

P21268

PISPPPSLK

10.79

-1.57

-2.88

LSKPISPPP

12.59

0.13

-1.18

SKPISPPPS

13.84

0.28

-1.03

P40091

QNPSHPHHN

13.33

-1.53

-2.84

PSHPHHNSR

13.72

-1.40

-2.71

P40450

SSPKLFPRL

8.28

-5.19

-6.50

APPPLPDLF

8.82

-3.88

-5.19

KLPQLPPPP

10.51

-2.29

-3.60

P32917

DYLPQHPHR

8.62

-3.78

-5.09

RFPPYSPLL

8.95

-0.46

-1.77

YLPQHPHRT

9.09

-4.06

-5.37

P25376

DRPSSQPHL

12.24

-2.91

-4.22

RPSSQPHLG

12.84

-1.67

-2.98

P40020

KSRVLPPLP

9.46

-2.09

-3.40

RPPPLTPEK

9.68

-2.08

-3.39

LPPLPFPLY

9.88

-2.77

-4.08

P41832

VIPPAPPMM

9.71

-2.90

-4.21

PPPPPVPAK

11.00

-0.06

-1.37

ETPPPPPLP

11.41

0.56

-0.75

P16892

TYHDPNDEP

11.83

-0.62

-1.93

EGEPIPPSF

13.31

-0.06

-1.37

P53947

PFNPIQDPF

11.31

-1.63

-2.94

ASPFNPIQD

13.35

1.00

-0.31

P34250

YPKEPPARK

8.83

-4.65

-5.96

LYPKEPPAR

9.76

-2.19

-3.50

YHSKKPSNP

11.33

-0.85

-2.16

P14681

DEPEYPPLN

10.93

-2.95

-4.26

EPEYPPLNL

13.71

-0.40

-1.71

Q12753

MMIKPKGRP

8.80

-4.66

-5.97

RYPPMAPTT

9.68

-0.44

-1.75

PRMPKTGSR

11.15

-0.84

-2.15

Q03466

SVPMAPDTF

13.59

-0.29

-1.60

P53950

PNGAPLRRY

9.60

-4.16

-5.47

PPAPLLPLP

10.31

-1.27

-2.58

NPNGAPLRR

10.42

-2.71

-4.02

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER