ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-21.PDB
Scoring matrix: FUS1_1FYN-21_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.86
Foldx random average score for Saccharomyces cerevisiae: 17.374

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1943665
Proteins after disorder filtering: 4469
 Total fragments: 81978
Proteins after pattern filtering: 1750
 Total fragments: 4643
Proteins after MINT filtering: 21
 Total fragments: 72


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

19.86

-0.62

0.00

Best peptides

EWRIGRPNWR

0.00

-2.62

-2.00

         
Interactors      
Q12280

PSKPGNNNSY

11.21

-3.68

-3.06

PLRPQSSSKI

13.11

-4.34

-3.72

VTPPLRPQSS

15.97

-2.32

-1.70

P31374

NISPERPSFR

10.81

-3.99

-3.37

PGTPVFPNLD

11.12

-3.98

-3.36

PPSPDQENHI

12.78

-3.76

-3.14

P36119

RPTVQPSNQS

13.04

-3.44

-2.82

TRPTVQPSNQ

16.78

-3.54

-2.92

P40073

GYPQQQPSHT

14.73

-2.55

-1.93

P24583

PPQPRKHDKT

14.34

-2.50

-1.88

PLPPQPRKHD

15.14

-4.27

-3.65

P39732

HPSIAPPSKL

13.62

-4.05

-3.43

RSPSVSPVRT

15.80

-3.41

-2.79

SPSVSPVRTT

16.27

-4.44

-3.82

P40091

SQNPSHPHHN

14.74

-1.69

-1.07

SPASSPVTWD

15.29

-1.80

-1.18

TWDPSSPSSV

15.99

-2.55

-1.93

P40450

SSPKLFPRLS

13.63

-4.41

-3.79

PPLPDLFKTK

14.96

-3.58

-2.96

PPLPESLSMN

14.98

-3.95

-3.33

P32917

DYLPQHPHRT

11.48

-2.17

-1.55

YLPQHPHRTS

14.85

-2.62

-2.00

PQHPHRTSSL

15.38

-3.20

-2.58

P25376

DRPSSQPHLG

15.06

-4.28

-3.66

P40020

PPYLSPQNKD

11.01

-6.26

-5.64

SEEPTSPTRQ

11.67

-4.22

-3.60

MSLPVTPVKS

14.47

-3.79

-3.17

P41832

PPPPLPSVLS

16.83

-4.68

-4.06

Q12114

SEPVGTPNIE

10.31

-6.04

-5.42

Q03466

PMAPDTFNVK

10.85

-5.26

-4.64

SVPMAPDTFN

13.47

-5.13

-4.51

SSVPMAPDTF

16.19

-1.29

-0.67

P14681

EPEYPPLNLD

16.03

-5.31

-4.69

P53046

PPTPKSAGHT

16.36

-4.05

-3.43

P53947

FNPIQDPFTD

13.49

-4.78

-4.16

NPIQDPFTDN

16.74

-1.82

-1.20

Q12753

IKPKGRPSTT

12.66

-3.93

-3.31

RYPPMAPTTV

13.47

-3.82

-3.20

INSPRMPKTG

13.89

-3.21

-2.59

P34250

SSNPDLPTAL

14.31

-2.95

-2.33

LYPKEPPARK

14.31

-4.19

-3.57

P53950

PSIPSASTST

15.06

-2.33

-1.71

NPNGAPLRRY

15.91

-2.80

-2.18

SNPNGAPLRR

16.17

-4.52

-3.90

P40210

EVDPTEPQTN

13.97

-3.60

-2.98

VDPTEPQTND

17.04

-2.72

-2.10

 


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