ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-20.PDB
Scoring matrix: FUS1_1FYN-20_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.54
Foldx random average score for Saccharomyces cerevisiae: 15.667

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1427064
Proteins after disorder filtering: 4542
 Total fragments: 73547
Proteins after pattern filtering: 1940
 Total fragments: 6720
Proteins after MINT filtering: 21
 Total fragments: 76


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.54

-1.29

0.00

Best peptides

RRPTKGMWW

0.00

-0.10

1.19

         
Interactors      
Q12280

SPSKPGNNN

14.06

-1.51

-0.22

NVTPPLRPQ

14.78

-2.33

-1.04

P36119

TRPTVQPSN

12.98

-0.77

0.52

P53046

PPTPKSAGH

14.38

-1.70

-0.41

TPPTPKSAG

14.48

-2.17

-0.88

P40073

GYPQQQPSH

14.20

-2.04

-0.75

P24583

LPPQPRKHD

11.41

-4.61

-3.32

APLPPQPRK

11.77

-3.95

-2.66

RANAPLPPQ

14.53

-4.21

-2.92

P39732

RHPSIAPPS

15.06

1.66

2.95

RSPSVSPVR

15.09

-0.08

1.21

P40091

NPSHPHHNS

13.73

-1.22

0.07

SQNPSHPHH

14.99

-4.08

-2.79

P40450

PPPLPDLFK

11.57

-6.54

-5.25

SSPKLFPRL

13.44

-0.46

0.83

APPLPNGLL

13.88

-3.85

-2.56

P32917

RFPPYSPLL

9.51

-2.93

-1.64

IPPKVAPFG

11.70

-2.86

-1.57

DYLPQHPHR

12.73

-3.83

-2.54

P25376

DRPSSQPHL

12.40

-1.85

-0.56

PSSQPHLGY

12.79

-3.73

-2.44

P40020

LPPLPFPLY

11.57

-4.15

-2.86

RVLPPLPFP

11.69

-4.32

-3.03

PPLTPEKNL

11.95

-5.74

-4.45

P41832

GVIPPAPPM

14.44

-4.58

-3.29

PPPPPMALF

14.69

-4.63

-3.34

PPPPMALFG

15.21

-1.73

-0.44

P16892

NDEPEGEPI

14.33

-2.75

-1.46

Q03466

VPMAPDTFN

15.19

-2.18

-0.89

Q12114

KSEPVGTPN

15.55

0.40

1.69

P31374

SPERPSFRQ

12.11

-3.39

-2.10

KPPPPLDFE

12.14

-4.39

-3.10

NISPERPSF

13.44

0.20

1.49

P53947

FNPIQDPFT

15.48

-3.91

-2.62

Q12753

INSPRMPKT

11.42

-2.58

-1.29

MIKPKGRPS

11.81

-1.65

-0.36

MMIKPKGRP

12.08

-6.90

-5.61

P34250

PKEPPARKS

14.76

-3.77

-2.48

ALYPKEPPA

15.22

-2.14

-0.85

P53950

APLLPLPSL

12.79

-4.19

-2.90

SNPNGAPLR

12.81

-1.21

0.08

PNGAPLRRY

13.12

-5.20

-3.91

P40210

DPTEPQTND

15.37

-1.68

-0.39

 


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