ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-2.PDB
Scoring matrix: FUS1_1FYN-2_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.32
Foldx random average score for Saccharomyces cerevisiae: 16.782

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1531464
Proteins after disorder filtering: 4484
 Total fragments: 82352
Proteins after pattern filtering: 2217
 Total fragments: 14213
Proteins after MINT filtering: 22
 Total fragments: 228


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.32

3.06

0.00

Best peptides

IRWRRWDRRR

0.00

1.17

-1.89

         
Interactors      
P36119

TRPTVQPSNQ

12.11

-1.52

-4.58

P53950

SNPNGAPLRR

10.77

-5.06

-8.12

NVVAPNPSIP

13.34

-4.56

-7.62

SNTPPAPLLP

13.59

-5.05

-8.11

P40073

DGYPQQQPSH

14.03

3.85

0.79

P24583

NAPLPPQPRK

11.25

-2.95

-6.01

ANAPLPPQPR

12.68

-3.71

-6.77

APLPPQPRKH

13.80

-4.52

-7.58

P53947

FNPIQDPFTD

15.08

1.17

-1.89

PFNPIQDPFT

16.39

3.51

0.45

P34250

YHSKKPSNPP

13.36

-3.05

-6.11

KKPSNPPSSG

13.78

0.27

-2.79

SALYPKEPPA

14.68

0.02

-3.04

P53046

TPPTPKSAGH

15.39

-1.56

-4.62

NQLSTPPTPK

16.58

-0.58

-3.64

Q12280

GTNVTPPLRP

13.10

-5.12

-8.18

VTPPLRPQSS

13.30

1.18

-1.88

TNINTAPASP

14.13

-2.31

-5.37

P39732

RHPSIAPPSK

12.37

0.17

-2.89

RSPSVSPVRT

14.33

-1.54

-4.60

HPSIAPPSKL

15.17

-4.13

-7.19

P40091

PSHPHHNSRP

13.26

-4.39

-7.45

NPSHPHHNSR

14.32

-4.33

-7.39

VTWDPSSPSS

15.32

1.02

-2.04

P40450

VSSSPKLFPR

12.30

-3.03

-6.09

SSPKLFPRLS

12.52

-2.28

-5.34

LVTPPAPPLP

12.96

-5.14

-8.20

P25376

DRPSSQPHLG

10.84

-4.51

-7.57

SNDRPSSQPH

13.98

-2.26

-5.32

GSNDRPSSQP

16.74

-0.98

-4.04

P41832

SVLSSQPPPP

13.33

-2.97

-6.03

DSPAPPPPPP

13.81

-1.68

-4.74

GVIPPAPPMM

13.94

-3.73

-6.79

Q03466

SVPMAPDTFN

13.22

-0.75

-3.81

SSVPMAPDTF

15.77

-2.16

-5.22

GSSVPMAPDT

16.11

-1.57

-4.63

P31374

FRKTKPPPPL

10.11

-3.64

-6.70

NISPERPSFR

11.65

-1.58

-4.64

PVFPNLDPTH

12.11

-3.01

-6.07

P32917

SRFPPYSPLL

11.50

-5.39

-8.45

DNIPPKVAPF

12.37

-0.08

-3.14

STDYLPQHPH

13.73

-1.50

-4.56

P40020

KKSRVLPPLP

10.18

-2.68

-5.74

SRVLPPLPFP

11.85

-1.62

-4.68

DRPPPLTPEK

12.53

-0.49

-3.55

P16892

DEPEGEPIPP

16.35

2.32

-0.74

PNDEPEGEPI

16.65

-3.42

-6.48

QTYHDPNDEP

16.76

-2.31

-5.37

P40210

EVDPTEPQTN

16.31

-0.88

-3.94

P21268

SKPISPPPSL

13.45

1.64

-1.42

KPISPPPSLK

14.00

-6.02

-9.08

PLNLSKPISP

14.51

-2.41

-5.47

Q12753

IKPKGRPSTT

10.70

-1.39

-4.45

HRYPPMAPTT

10.72

-1.26

-4.32

INSPRMPKTG

11.15

-1.34

-4.40

P14681

YHDPSDEPEY

16.11

1.17

-1.89

DPSDEPEYPP

16.28

-4.85

-7.91

DEPEYPPLNL

16.30

2.04

-1.02

 


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