ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-18.PDB
Scoring matrix: FUS1_1FYN-18_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 19.7
Foldx random average score for Saccharomyces cerevisiae: 17.593

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199860
Proteins after random average filtering: 7178
 Total fragments: 1332849
Proteins after disorder filtering: 4450
 Total fragments: 71531
Proteins after pattern filtering: 2107
 Total fragments: 10662
Proteins after MINT filtering: 23
 Total fragments: 139


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

19.70

0.51

0.00

Best peptides

RWPRKSIHYY

0.00

-1.06

-1.57

         
Interactors      
P36119

RPTVQPSNQS

15.82

-1.48

-1.99

STTRPTVQPS

15.83

-0.81

-1.32

P53950

SNPNGAPLRR

14.34

-1.34

-1.85

PNGAPLRRYS

15.54

-2.40

-2.91

TKTAPSTAPL

16.12

-0.63

-1.14

P40073

FDGYPQQQPS

13.89

-0.90

-1.41

P24583

LPPQPRKHDK

13.26

-4.65

-5.16

NAPLPPQPRK

13.91

-3.86

-4.37

ANAPLPPQPR

15.79

-2.16

-2.67

P53947

FNPIQDPFTD

17.43

0.09

-0.42

P34250

HSKKPSNPPS

12.60

-2.63

-3.14

LYPKEPPARK

13.68

-3.69

-4.20

KPSNPPSSGN

14.90

-1.29

-1.80

P53046

TPPTPKSAGH

14.43

-1.56

-2.07

NQLSTPPTPK

15.90

-2.14

-2.65

PPTPKSAGHT

17.53

-1.69

-2.20

Q12280

YSGSPSKPGN

14.05

-1.60

-2.11

TNVTPPLRPQ

14.62

-1.33

-1.84

SPSKPGNNNS

15.43

-0.85

-1.36

P39732

RSPSVSPVRT

13.09

-2.09

-2.60

SSRSPSVSPV

13.80

-1.11

-1.62

HPSIAPPSKL

13.89

-1.45

-1.96

P40091

SPASSPVTWD

15.25

-1.29

-1.80

DPSSPSSVGS

15.64

0.16

-0.35

SQNPSHPHHN

16.40

-2.68

-3.19

P40450

VSSSPKLFPR

13.60

-1.58

-2.09

APPPLPDLFK

14.42

-2.00

-2.51

PPPLPDLFKT

14.83

-3.82

-4.33

P25376

RPSSQPHLGY

10.61

-3.24

-3.75

SNDRPSSQPH

11.89

-1.14

-1.65

P41832

PPPLPSVLSS

13.47

-2.47

-2.98

IPPAPPMMPA

14.38

-3.04

-3.55

KGETPPPPPL

15.75

-3.86

-4.37

Q03466

SVPMAPDTFN

15.51

-2.77

-3.28

P31374

FRKTKPPPPL

13.18

-4.67

-5.18

FPNLDPTHSQ

13.86

-4.33

-4.84

GNNISPERPS

14.29

-1.45

-1.96

P32917

YSPLLPPFGL

11.89

-3.65

-4.16

STDYLPQHPH

12.94

-1.75

-2.26

QSRFPPYSPL

13.36

-3.25

-3.76

P40020

LPPLPFPLYD

10.88

-4.89

-5.40

LPPYLSPQNK

11.88

-3.31

-3.82

KSRVLPPLPF

12.27

-3.30

-3.81

P16892

HDPNDEPEGE

17.02

1.18

0.67

P40210

HDEVDPTEPQ

17.46

-0.07

-0.58

Q12114

GHETAPVSPV

16.09

-0.29

-0.80

LKSEPVGTPN

17.10

-2.28

-2.79

P21268

LNLSKPISPP

15.24

0.17

-0.34

LSKPISPPPS

16.08

-2.15

-2.66

SKPISPPPSL

16.77

-1.78

-2.29

Q12753

RNDLPDTSPM

12.02

-3.11

-3.62

MMIKPKGRPS

13.79

-4.15

-4.66

NHRYPPMAPT

14.05

-4.66

-5.17

P14681

PSDEPEYPPL

17.00

-0.02

-0.53

 


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