ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-17.PDB
Scoring matrix: FUS1_1FYN-17_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.06
Foldx random average score for Saccharomyces cerevisiae: 15.069

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3207038
Proteins after random average filtering: 7178
 Total fragments: 1346521
Proteins after disorder filtering: 4447
 Total fragments: 57373
Proteins after pattern filtering: 1825
 Total fragments: 5557
Proteins after MINT filtering: 17
 Total fragments: 66


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.06

-0.68

0.00

Best peptides

RWRYKGMRM

0.00

-2.17

-1.49

         
Interactors      
Q12280

SPSKPGNNN

13.53

-1.89

-1.21

NVTPPLRPQ

13.79

-1.23

-0.55

APASPEEPK

13.92

-0.51

0.17

P31374

SPERPSFRQ

9.91

-1.06

-0.38

KPPPPLDFE

10.59

-2.90

-2.22

VFPNLDPTH

13.08

-0.43

0.25

P53046

LSTPPTPKS

12.97

-1.29

-0.61

PPTPKSAGH

13.72

0.04

0.72

TPPTPKSAG

14.83

-0.69

-0.01

P24583

APLPPQPRK

10.61

-2.50

-1.82

RANAPLPPQ

12.73

-2.35

-1.67

LPPQPRKHD

13.72

-2.93

-2.25

P39732

RSPSVSPVR

12.32

-0.49

0.19

RHPSIAPPS

14.24

-0.02

0.66

P40091

NPSHPHHNS

13.10

-2.52

-1.84

SQNPSHPHH

13.83

-2.67

-1.99

P40450

PPPLPDLFK

11.38

-5.66

-4.98

SSPKLFPRL

11.62

-1.34

-0.66

PPLPNGLLS

13.50

-1.62

-0.94

P32917

RFPPYSPLL

10.82

-3.15

-2.47

IPPKVAPFG

10.94

-2.44

-1.76

DYLPQHPHR

11.44

-4.08

-3.40

P25376

DRPSSQPHL

14.31

-2.30

-1.62

P40020

RPPPLTPEK

11.79

-0.11

0.57

LPPYLSPQN

11.79

-3.76

-3.08

PPLTPEKNL

11.81

-3.78

-3.10

P41832

GVIPPAPPM

13.39

-3.68

-3.00

PPPPPVPAK

14.02

-2.29

-1.61

PPPPPMALF

14.20

-3.29

-2.61

Q12114

KSEPVGTPN

13.95

0.04

0.72

Q03466

VPMAPDTFN

12.42

-2.99

-2.31

P53947

FNPIQDPFT

14.11

-3.71

-3.03

Q12753

MIKPKGRPS

10.70

-1.93

-1.25

INSPRMPKT

13.04

-1.94

-1.26

PRMPKTGSR

13.78

-2.48

-1.80

P34250

PKEPPARKS

13.77

-1.92

-1.24

ALYPKEPPA

14.57

-1.90

-1.22

P53950

PNGAPLRRY

12.62

-2.47

-1.79

DSNPNGAPL

13.14

-1.13

-0.45

APLLPLPSL

13.67

-3.61

-2.93

 


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