ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-13.PDB
Scoring matrix: FUS1_1FYN-13_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.58
Foldx random average score for Saccharomyces cerevisiae: 14.379

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1355822
Proteins after disorder filtering: 4629
 Total fragments: 87309
Proteins after pattern filtering: 2205
 Total fragments: 13461
Proteins after MINT filtering: 23
 Total fragments: 198


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.58

-0.88

0.00

Best peptides

RFRWRRWW

0.00

-0.63

0.25

         
Interactors      
P36119

RPTVQPSN

11.24

-3.48

-2.60

PTVQPSNQ

12.36

-3.66

-2.78

TRPTVQPS

14.31

-1.75

-0.87

P53950

APLLPLPS

10.67

-3.57

-2.69

TPPAPLLP

13.08

-1.81

-0.93

PNPSIPSA

13.19

-1.49

-0.61

P40073

YPQQQPSH

12.39

-2.55

-1.67

P24583

RANAPLPP

11.76

-3.14

-2.26

LPPQPRKH

13.00

-4.59

-3.71

APLPPQPR

13.56

-2.51

-1.63

P53947

PIQDPFTD

13.62

-1.89

-1.01

ASPFNPIQ

13.64

-3.34

-2.46

P34250

HSKKPSNP

8.81

-6.27

-5.39

YPKEPPAR

10.36

-3.70

-2.82

NPDLPTAL

10.83

-4.03

-3.15

P53046

LSTPPTPK

13.44

-1.93

-1.05

QLSTPPTP

13.66

-3.63

-2.75

TPPTPKSA

13.72

-1.86

-0.98

Q12280

SPSKPGNN

10.40

-4.28

-3.40

TPPLRPQS

11.59

-3.79

-2.91

INTAPASP

13.17

-1.14

-0.26

P39732

RHPSIAPP

10.10

-3.81

-2.93

SPSVSPVR

11.65

-1.83

-0.95

RSPSVSPV

12.33

-3.44

-2.56

P40091

SPASSPVT

12.69

-0.78

0.10

PASSPVTW

13.57

-1.21

-0.33

WDPSSPSS

13.88

-0.23

0.65

P40450

LPQLPPPP

9.66

-4.52

-3.64

PPPLPDLF

11.05

-4.84

-3.96

PPPLPESL

11.11

-3.75

-2.87

P25376

RPSSQPHL

13.23

-4.74

-3.86

P41832

PPPLPSVL

9.18

-4.88

-4.00

PPPPPPVP

11.07

-3.70

-2.82

APPMMPAS

11.24

-3.59

-2.71

Q03466

VPMAPDTF

13.27

-1.73

-0.85

GSSVPMAP

13.57

-1.99

-1.11

P31374

RKTKPPPP

8.04

-6.08

-5.20

DFEQPRLP

10.45

-3.68

-2.80

QPRLPSTA

10.72

-3.61

-2.73

P32917

RFPPYSPL

8.58

-5.28

-4.40

FPPYSPLL

10.93

-2.90

-2.02

SPLLPPFG

11.60

-5.72

-4.84

P40020

LPPLPFPL

9.44

-4.35

-3.47

SRVLPPLP

10.41

-5.44

-4.56

RVLPPLPF

10.89

-4.51

-3.63

P16892

YHDPNDEP

12.65

-0.90

-0.02

EGEPIPPS

14.29

-1.13

-0.25

PEGEPIPP

14.29

-1.23

-0.35

P40210

DPTEPQTN

13.96

-1.51

-0.63

PTEPQTND

14.19

-1.70

-0.82

Q12114

EPVGTPNI

12.29

-2.42

-1.54

HETAPVSP

12.66

-2.70

-1.82

P21268

KPISPPPS

11.94

-2.55

-1.67

NLSKPISP

12.81

-3.01

-2.13

LSKPISPP

13.16

-2.39

-1.51

Q12753

YPPMAPTT

10.19

-3.13

-2.25

INSPRMPK

10.81

-0.95

-0.07

SPRMPKTG

10.89

-3.55

-2.67

P14681

EPEYPPLN

12.03

-4.21

-3.33

PEYPPLNL

12.82

-3.17

-2.29

YHDPSDEP

13.58

-1.10

-0.22

 


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