ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-12.PDB
Scoring matrix: FUS1_1FYN-12_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.57
Foldx random average score for Saccharomyces cerevisiae: 8.169

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1301487
Proteins after disorder filtering: 4592
 Total fragments: 71321
Proteins after pattern filtering: 2197
 Total fragments: 13363
Proteins after MINT filtering: 22
 Total fragments: 207


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.57

-1.29

0.00

Best peptides

RWIMDMWR

0.00

-1.00

0.29

         
Interactors      
P36119

TRPTVQPS

7.26

-2.34

-1.05

TTRPTVQP

7.38

-2.48

-1.19

P53950

NTPPAPLL

6.34

-2.97

-1.68

PSIPSAST

6.42

-3.42

-2.13

TPPAPLLP

7.02

-3.13

-1.84

P40073

DGYPQQQP

7.14

-2.19

-0.90

GYPQQQPS

7.42

-1.16

0.13

P24583

PLPPQPRK

6.17

-3.38

-2.09

LPPQPRKH

6.40

-4.02

-2.73

RANAPLPP

6.84

-3.74

-2.45

P53947

NPIQDPFT

5.74

-4.09

-2.80

ASPFNPIQ

7.31

-2.02

-0.73

PIQDPFTD

7.40

-2.70

-1.41

P34250

SSNPDLPT

5.75

-3.49

-2.20

SKKPSNPP

5.94

-3.82

-2.53

ALYPKEPP

6.86

-2.74

-1.45

P53046

STPPTPKS

6.81

-3.38

-2.09

LSTPPTPK

7.51

-2.93

-1.64

TPPTPKSA

7.83

-2.34

-1.05

Q12280

VTPPLRPQ

4.90

-4.58

-3.29

NVTPPLRP

5.11

-4.78

-3.49

GSPSKPGN

7.16

-2.17

-0.88

P39732

PSVSPVRT

5.05

-3.81

-2.52

PSIAPPSK

5.21

-4.22

-2.93

TRHPSIAP

6.62

-3.28

-1.99

P40091

QNPSHPHH

6.65

-1.83

-0.54

PSHPHHNS

6.89

-3.62

-2.33

SQNPSHPH

6.94

-4.00

-2.71

P40450

GAVPPPPP

5.03

-4.42

-3.13

PAPPPLPD

5.29

-4.13

-2.84

SSPKLFPR

5.39

-2.83

-1.54

P25376

DRPSSQPH

6.33

-2.53

-1.24

PSSQPHLG

7.98

-2.05

-0.76

P41832

GVIPPAPP

5.23

-3.97

-2.68

PAPPMMPA

5.48

-4.09

-2.80

ETPPPPPL

5.64

-3.87

-2.58

Q03466

SVPMAPDT

6.92

-1.84

-0.55

SSVPMAPD

7.19

-3.23

-1.94

GSSVPMAP

7.41

-2.23

-0.94

P31374

NNISPERP

4.60

-2.40

-1.11

PERPSFRQ

4.76

-4.05

-2.76

PVFPNLDP

5.48

-3.81

-2.52

P32917

SRFPPYSP

4.80

-4.14

-2.85

PQHPHRTS

5.96

-4.37

-3.08

PPYSPLLP

5.99

-3.87

-2.58

P40020

DRPPPLTP

5.43

-4.43

-3.14

RVLPPLPF

5.43

-4.19

-2.90

PLPFPLYD

5.86

-3.93

-2.64

P16892

GEPIPPSF

7.60

-2.78

-1.49

EGEPIPPS

7.60

-3.83

-2.54

HDPNDEPE

7.87

-1.02

0.27

P40210

VDPTEPQT

7.89

-2.35

-1.06

P21268

KPISPPPS

6.79

-4.39

-3.10

SKPISPPP

7.08

-2.72

-1.43

PISPPPSL

7.92

-2.18

-0.89

Q12753

HRYPPMAP

4.22

-4.99

-3.70

IKPKGRPS

5.60

-4.27

-2.98

INSPRMPK

6.05

-3.35

-2.06

P14681

PEYPPLNL

5.65

-4.01

-2.72

SDEPEYPP

6.82

-3.85

-2.56

HDPSDEPE

7.01

-0.82

0.47

 


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