ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-11.PDB
Scoring matrix: FUS1_1FYN-11_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.05
Foldx random average score for Saccharomyces cerevisiae: 9.758

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221394
Proteins after random average filtering: 7178
 Total fragments: 1518682
Proteins after disorder filtering: 4804
 Total fragments: 88012
Proteins after pattern filtering: 2161
 Total fragments: 10626
Proteins after MINT filtering: 22
 Total fragments: 166


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.05

-1.09

0.00

Best peptides

FRPMPRL

0.00

-3.78

-2.69

         
Interactors      
P36119

RPTVQPS

6.91

-4.24

-3.15

PTVQPSN

8.94

-1.95

-0.86

P53950

APLLPLP

6.79

-3.71

-2.62

NPSIPSA

7.28

-2.89

-1.80

PAPLLPL

7.72

-3.29

-2.20

P40073

YPQQQPS

8.37

-1.97

-0.88

P24583

NAPLPPQ

6.50

-2.68

-1.59

ANAPLPP

7.86

-2.63

-1.54

LPPQPRK

7.88

-3.07

-1.98

P53947

FNPIQDP

4.73

-3.28

-2.19

ASPFNPI

7.32

-2.05

-0.96

SPFNPIQ

8.26

-1.68

-0.59

P34250

KPSNPPS

4.75

-2.04

-0.95

KKPSNPP

6.57

-1.60

-0.51

KPAYVPP

7.14

-2.68

-1.59

P53046

TPPTPKS

8.36

-0.56

0.53

LSTPPTP

9.56

-2.40

-1.31

Q12280

SPSKPGN

7.05

-2.61

-1.52

TPPLRPQ

7.12

-1.54

-0.45

PPLRPQS

7.51

-3.47

-2.38

P39732

RHPSIAP

7.67

-1.51

-0.42

HPSIAPP

8.38

-1.74

-0.65

RSPSVSP

9.04

-0.59

0.50

P40091

DPSSPSS

8.88

-0.53

0.56

WDPSSPS

9.39

1.30

2.39

P40450

PKLFPRL

6.17

-4.38

-3.29

PPPLPDL

6.39

-4.83

-3.74

LPQLPPP

6.43

-4.82

-3.73

P25376

PSSQPHL

8.82

-2.64

-1.55

P41832

IPPAPPM

6.60

-2.72

-1.63

PPMMPAS

6.82

-4.08

-2.99

PPPLPSV

6.93

-3.19

-2.10

Q03466

VPMAPDT

9.17

-1.03

0.06

P31374

ISPERPS

6.64

0.32

1.41

EQPRLPS

6.71

-0.74

0.35

KPGTPVF

6.93

-1.40

-0.31

P32917

FPPYSPL

5.84

-2.16

-1.07

YSPLLPP

6.54

-3.47

-2.38

IPPKVAP

7.23

-2.17

-1.08

P40020

LPPLPFP

6.08

-4.44

-3.35

RPPPLTP

7.04

-3.93

-2.84

RVLPPLP

7.16

-3.31

-2.22

P16892

GEPIPPS

6.23

-2.05

-0.96

EPIPPSF

8.45

-1.26

-0.17

PNDEPEG

9.70

-1.85

-0.76

P40210

DPTEPQT

9.63

-1.32

-0.23

P21268

KPISPPP

6.94

-1.93

-0.84

PISPPPS

8.61

-1.58

-0.49

SKPISPP

8.88

-0.44

0.65

Q12753

IPQSPPL

6.74

-2.37

-1.28

INSPRMP

6.74

-2.46

-1.37

YPPMAPT

6.91

-2.20

-1.11

P14681

EPEYPPL

6.66

-3.37

-2.28

 


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