ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-10.PDB
Scoring matrix: FUS1_1FYN-10_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.18
Foldx random average score for Saccharomyces cerevisiae: 11.108

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214216
Proteins after random average filtering: 7178
 Total fragments: 1287599
Proteins after disorder filtering: 4500
 Total fragments: 64761
Proteins after pattern filtering: 2136
 Total fragments: 10840
Proteins after MINT filtering: 22
 Total fragments: 167


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.18

-0.66

0.00

Best peptides

FHRWHRKP

0.00

-0.49

0.17

         
Interactors      
P36119

RPTVQPSN

8.19

-2.03

-1.37

PTVQPSNQ

10.71

-2.03

-1.37

P53950

NPSIPSAS

8.89

-3.33

-2.67

PAPLLPLP

9.52

-3.01

-2.35

TPPAPLLP

9.62

-3.48

-2.82

P40073

YPQQQPSH

9.93

-1.56

-0.90

P24583

LPPQPRKH

7.21

-5.57

-4.91

NAPLPPQP

9.92

-3.55

-2.89

PPQPRKHD

10.88

-2.67

-2.01

P53947

FNPIQDPF

8.78

-3.97

-3.31

ASPFNPIQ

8.98

-3.78

-3.12

SPFNPIQD

10.42

-3.84

-3.18

P34250

HSKKPSNP

7.45

-5.26

-4.60

YPKEPPAR

8.56

-3.80

-3.14

NPDLPTAL

9.01

-3.56

-2.90

P53046

PPTPKSAG

9.79

-1.86

-1.20

STPPTPKS

10.69

-0.81

-0.15

LSTPPTPK

10.99

-2.29

-1.63

Q12280

YSGSPSKP

7.21

-3.27

-2.61

TPPLRPQS

8.26

-5.12

-4.46

PPLRPQSS

8.67

-3.87

-3.21

P39732

HPSIAPPS

9.15

-6.07

-5.41

PSVSPVRT

10.38

-3.01

-2.35

PSIAPPSK

10.57

-1.61

-0.95

P40091

QNPSHPHH

8.51

-0.98

-0.32

PSHPHHNS

9.63

-0.41

0.25

VTWDPSSP

10.62

-2.03

-1.37

P40450

SPKLFPRL

6.98

-3.80

-3.14

PPPLPDLF

8.36

-5.60

-4.94

PKLFPRLS

8.60

-5.28

-4.62

P25376

RPSSQPHL

9.35

-0.58

0.08

PSSQPHLG

10.89

-3.79

-3.13

P41832

PPPVPAKL

7.20

-3.38

-2.72

PPAPPMMP

8.47

-4.01

-3.35

PPPPPPMA

8.54

-4.64

-3.98

Q03466

GSSVPMAP

9.74

-2.80

-2.14

P31374

SPERPSFR

6.44

-3.68

-3.02

TPVFPNLD

7.88

-5.18

-4.52

QPRLPSTA

8.25

-4.70

-4.04

P32917

SPLLPPFG

6.91

-4.69

-4.03

FPPYSPLL

7.75

-3.63

-2.97

YLPQHPHR

8.49

-1.58

-0.92

P40020

SRVLPPLP

7.35

-5.36

-4.70

PHSIPFSV

7.70

-3.44

-2.78

CVNPHSIP

8.18

-0.16

0.50

P16892

YHDPNDEP

10.12

-0.72

-0.06

GEPIPPSF

10.27

-3.22

-2.56

Q12114

HETAPVSP

10.32

-1.86

-1.20

P21268

KPISPPPS

10.47

-3.29

-2.63

NLSKPISP

10.78

-1.84

-1.18

Q12753

NSPRMPKT

6.82

-2.81

-2.15

HRYPPMAP

7.65

-4.49

-3.83

MIKPKGRP

9.21

-5.36

-4.70

P14681

EPEYPPLN

7.87

-3.67

-3.01

PSDEPEYP

10.65

-3.33

-2.67

YHDPSDEP

10.71

-1.03

-0.37

 


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