ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BZZ1-D2_1ZUU-23.PDB
Scoring matrix: BZZ1-D2_1ZUU-23_mat
Uniprot code: P38822
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.8
Foldx random average score for Saccharomyces cerevisiae: 12.555

Available information for P38822 in MINT (Nov 2008):
Nš of interacting proteins: 129
 Proteins belonging to other specie: 0
Nš of interactions described: 162
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221273
Proteins after random average filtering: 7178
 Total fragments: 1853553
Proteins after disorder filtering: 4933
 Total fragments: 149370
Proteins after pattern filtering: 2183
 Total fragments: 9136
Proteins after MINT filtering: 42
 Total fragments: 299


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.80

-0.18

0.00

Best peptides

RPRMPRE

0.00

2.59

2.77

         
Interactors      
Q06604

GPRMPSR

7.29

-1.55

-1.37

NKPKPTP

8.64

-2.42

-2.24

LPTRPNK

8.82

-4.11

-3.93

P24814

HPPDIHP

8.44

-0.31

-0.13

IHPNLGP

8.54

-0.40

-0.22

PNLGPQL

9.52

-2.86

-2.68

P53142

PLIEPTT

11.75

0.42

0.60

P32571

SSPSPLP

6.24

-3.01

-2.83

LPINYPE

9.04

-1.38

-1.20

PLHSPDP

9.75

-1.95

-1.77

Q06412

SPKSPRD

5.80

-2.26

-2.08

SPNSPKS

9.67

-2.75

-2.57

NSPKSPR

9.91

-1.29

-1.11

Q12034

PTTSPWK

7.96

-2.33

-2.15

GYPNFFP

9.32

-1.05

-0.87

P32578

VHPQEPP

9.03

-0.68

-0.50

ERPSTPF

10.11

-1.84

-1.66

HPQEPPS

10.29

1.54

1.72

Q12451

PKHAPPP

7.88

-3.55

-3.37

AAPKHAP

8.71

-0.64

-0.46

PHLLPWL

10.48

-4.04

-3.86

P15891

PEKKPKE

6.51

-1.68

-1.50

TPEKKPK

6.81

-1.70

-1.52

KTPSPAP

8.47

-2.01

-1.83

P39005

ATPASMP

8.24

-4.77

-4.59

PASMPSD

9.98

-1.86

-1.68

TPASMPS

10.97

-0.68

-0.50

Q04052

PVDNPHD

10.81

0.95

1.13

NPHDPPC

11.74

1.06

1.24

Q08912

HPKGPPP

5.90

-2.84

-2.66

PSWGPSP

8.36

-2.20

-2.02

DHPKGPP

9.51

-2.26

-2.08

P17555

RPKKPST

7.34

-3.47

-3.29

PPPRPKK

7.46

-3.78

-3.60

AAPAPPP

8.21

-3.82

-3.64

Q12342

ETPSTPS

12.38

-0.45

-0.27

P24276

KPPQSPK

7.98

-2.05

-1.87

PPQSPKI

10.05

-1.12

-0.94

FTPQPPH

10.28

-0.20

-0.02

P53080

PPPQTLP

6.73

-1.81

-1.63

SPPSSPS

10.36

-1.51

-1.33

PPSSPSS

11.61

-1.16

-0.98

P89495

NLPSHYP

8.28

-0.64

-0.46

YPTSPLV

9.46

-2.24

-2.06

LRPCLTP

9.48

-2.12

-1.94

P40096

PPIKPEH

9.28

-3.27

-3.09

P36125

LPAGPQG

10.06

-1.65

-1.47

P36006

PPPMGQP

7.70

-2.75

-2.57

PPMGQPK

7.85

-2.24

-2.06

KPKNPGG

8.23

-0.24

-0.06

P32790

PPIKPPR

8.34

-1.95

-1.77

KPPRPTS

8.48

-3.83

-3.65

PPAMPAR

8.73

-2.65

-2.47

P53939

SQPGSLP

5.34

-2.89

-2.71

KLPKSQP

7.13

-3.84

-3.66

PKSQPGS

9.97

0.56

0.74

P25614

KTPGGPF

7.60

-2.62

-2.44

SNPCQPA

10.33

-1.67

-1.49

GPLSNPC

11.13

-2.05

-1.87

P32505

YPNCPKP

8.25

-4.05

-3.87

FPHCPLG

8.41

-2.07

-1.89

CPFGHPT

9.28

0.15

0.33

P53933

DLPMELP

7.04

-1.76

-1.58

SYPGNPT

9.04

-1.62

-1.44

LPMELPH

10.10

-0.59

-0.41

P32386

PPPQWPQ

11.11

-0.58

-0.40

P40020

TPESPLN

7.15

-2.09

-1.91

TPPAPTS

9.57

-2.75

-2.57

PTSAPSI

10.32

-2.53

-2.35

P32639

KLPKKFP

6.12

-4.88

-4.70

LPKKFPP

7.49

-1.31

-1.13

Q04439

KKPAPPP

6.42

-4.42

-4.24

KPKEPMF

6.50

-4.04

-3.86

SKPKEPM

7.23

-2.03

-1.85

Q12446

PRRGPAP

6.25

-2.33

-2.15

PPPRRGP

6.52

-1.93

-1.75

APSAPIP

6.56

-3.48

-3.30

P43580

MPKSRPK

8.54

-3.48

-3.30

P35193

DPVSPKA

12.29

-0.73

-0.55

P39940

PSSSPHS

11.00

-0.60

-0.42

DDPRLPS

11.24

-1.35

-1.17

P38266

TPPRPPP

5.96

-2.48

-2.30

KDPKSFP

5.99

-4.56

-4.38

SPKKVPP

6.26

-4.14

-3.96

P53264

SRPKFPF

7.22

-1.99

-1.81

KFPFEYP

10.45

-1.04

-0.86

RPKFPFE

10.49

-1.36

-1.18

Q08989

HPKGPPP

5.90

-2.84

-2.66

DHPKGPP

9.51

-2.26

-2.08

Q7LHG5

KSPCSSP

8.09

-3.30

-3.12

VPSKSPC

10.09

0.35

0.53

SPCSSPV

10.28

-2.14

-1.96

P00812

VPHCPES

10.97

-0.71

-0.53

VDPLYIP

11.19

-3.89

-3.71

P37370

QMPKPRP

3.53

-1.99

-1.81

KVPQNRP

4.31

-2.37

-2.19

IPLAPLP

5.15

-5.03

-4.85

P40187

EPLNLPN

10.41

-1.43

-1.25

GNPSPPI

11.18

-1.83

-1.65

DEPLNLP

11.88

-4.43

-4.25

P11792

PPFKPHL

8.27

-1.88

-1.70

GNPNLPP

10.07

-0.28

-0.10

FIPGNPN

10.40

-1.72

-1.54

P40453

TTPEIPP

8.76

-1.32

-1.14

EPPSWKP

9.14

-2.43

-2.25

CPRCGPT

9.21

-0.59

-0.41

 


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