ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BZZ1-D1_2A28-29.PDB
Scoring matrix: BZZ1-D1_2A28-29_mat
Uniprot code: P38822
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.17
Foldx random average score for Saccharomyces cerevisiae: 13.226

Available information for P38822 in MINT (Nov 2008):
Nš of interacting proteins: 129
 Proteins belonging to other specie: 0
Nš of interactions described: 162
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199739
Proteins after random average filtering: 7177
 Total fragments: 1566485
Proteins after disorder filtering: 4265
 Total fragments: 62798
Proteins after pattern filtering: 2138
 Total fragments: 13676
Proteins after MINT filtering: 45
 Total fragments: 687


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.17

0.49

0.00
Best peptides

DFFPIPPHRK

0.00

-7.50

-7.99
         
Interactors      
Q06604

SPPPLPTRRD

6.19

-9.51

-10.00

TPPSPPAKRI

7.39

-7.90

-8.39

EKPLLPTRPN

7.49

-9.21

-9.70
P33419

RLPPPPFSSY

11.00

-6.65

-7.14

TRLPPPPFSS

11.11

-7.08

-7.57

PPPPFSSYGM

11.88

-3.73

-4.22
P24814

HPPDIHPNLG

10.13

-9.68

-10.17

RLHPPDIHPN

10.16

-5.72

-6.21

NNSTRPQMPS

11.34

-5.31

-5.80
P32571

INYPETPHLW

8.51

-7.42

-7.91

NYPETPHLWK

10.07

-6.32

-6.81

SPSPLPLHSP

11.10

-7.00

-7.49
Q06412

EFFTKPPPPL

8.28

-6.64

-7.13

PPPPLSTSRN

9.34

-5.32

-5.81

RPPPPPPLLY

10.28

-8.59

-9.08
Q12034

SYMGYPNFFP

10.55

-6.65

-7.14

YPNFFPSNEN

10.93

-5.06

-5.55

GYPNFFPSNE

11.65

-4.62

-5.11
P32578

LQPLHPLHPI

7.51

-7.56

-8.05

VHPQEPPSFT

10.96

-6.59

-7.08

DSDDVHPQEP

11.53

-4.23

-4.72
Q12451

HLLPWLPPTD

11.70

-6.27

-6.76

LLPWLPPTDT

11.77

-6.25

-6.74

APPPVPNETD

11.80

-5.69

-6.18
P15891

AAPPPPPRRA

6.97

-9.66

-10.15

AQPPLPSRNV

8.79

-8.74

-9.23

ATPEKKPKEN

8.95

-7.10

-7.59
P39005

VNYATPASMP

12.20

-5.58

-6.07
Q04052

LGPVDNPHDP

11.85

-4.52

-5.01

CDLGPVDNPH

12.47

-6.54

-7.03
Q08912

PPPPDEKDRG

11.37

-3.61

-4.10

PPPPPDEKDR

11.89

-5.25

-5.74

KGPPPPPPPD

12.25

-6.16

-6.65
P17555

GPPPRPKKPS

6.91

-8.51

-9.00

SKSGPPPRPK

9.84

-7.22

-7.71

SGPPPRPKKP

9.92

-6.90

-7.39
P47075

VDIRKPPLPT

8.75

-6.89

-7.38

RKPPLPTNIE

8.88

-8.49

-8.98

DIRKPPLPTN

13.16

-4.08

-4.57
Q12342

KAPPPPPPPP

12.07

-6.85

-7.34

APPPPPPPPP

12.11

-6.80

-7.29

KAKAPPPPPP

12.42

-5.08

-5.57
P24276

HFTPQPPHPH

7.37

-7.29

-7.78

NKPPQSPKIA

8.17

-7.15

-7.64

SDFKFPPPPN

9.46

-5.83

-6.32
P53080

DIPPPQTLPN

11.62

-6.19

-6.68

SPPSSPSSTT

12.40

-4.02

-4.51

HSPPSSPSST

12.58

-3.14

-3.63
P89495

LSLNLPSHYP

9.18

-6.94

-7.43

TIPPLPTTIH

10.12

-7.06

-7.55

SHSTIPPLPT

10.68

-6.92

-7.41
P47003

STLSIPHPTP

12.13

-5.73

-6.22
P40096

LPPIKPEHEV

6.99

-6.79

-7.28

QLPPIKPEHE

9.82

-7.75

-8.24

PIKPEHEVPL

11.64

-3.37

-3.86
P36125

PAGPQGQRRR

11.35

-6.39

-6.88

DLPAGPQGQR

11.62

-6.90

-7.39

LPAGPQGQRR

12.81

-4.85

-5.34
P36006

GQPKDPKFEA

9.58

-7.88

-8.37

ANIPIPPPPP

9.59

-8.29

-8.78

KSNKKPKNPG

10.40

-4.33

-4.82
P32790

PPPAMPARPT

7.15

-8.94

-9.43

LPPIKPPRPT

7.29

-9.18

-9.67

PAPLDPFKTG

10.10

-5.93

-6.42
P53939

NPIIIPDSQD

10.35

-5.71

-6.20

YPPTLFPPPL

11.78

-6.37

-6.86

LPKSQPGSLP

12.20

-4.58

-5.07
P25614

GPLSNPCQPA

12.11

-6.02

-6.51
P32505

LFPHCPLGRS

9.48

-6.50

-6.99

NEYPNCPKPP

9.83

-5.51

-6.00

GRCRLFPHCP

10.28

-5.92

-6.41
P53933

APPPLPNRQL

8.38

-8.92

-9.41

PPPPIPSTQK

9.25

-7.99

-8.48

VAPPPLPNRQ

9.80

-10.09

-10.58
P32386

KEIPPPQWPQ

11.88

-5.64

-6.13

HKEIPPPQWP

12.09

-5.69

-6.18

EIPPPQWPQD

13.10

-4.94

-5.43
P40020

EEPTSPTRQV

8.45

-7.75

-8.24

KSRVLPPLPF

9.59

-6.37

-6.86

VLPPLPFPLY

10.03

-8.53

-9.02
P32639

KLPKKFPPPT

9.56

-7.35

-7.84

GFKLPKKFPP

10.59

-5.92

-6.41

KFPPPTPLLE

11.14

-7.03

-7.52
Q04439

PPPPPSSKPK

9.12

-6.09

-6.58

NIPTPPQNRD

9.30

-9.33

-9.82

SKPKEPMFEA

9.87

-7.87

-8.36
Q12446

PAPPPPPHRH

5.27

-8.92

-9.41

PAPPPPPRRG

7.02

-10.37

-10.86

PVPPPPPMRT

8.39

-9.00

-9.49
P35193

HEDPVSPKAG

8.66

-3.34

-3.83

EDPVSPKAGS

12.22

-4.77

-5.26
P39940

DDPRLPSSLD

9.58

-6.78

-7.27

WDDPRLPSSL

10.97

-5.81

-6.30

TTWDDPRLPS

11.33

-5.93

-6.42
P38266

SLPPPPTHRD

4.85

-9.30

-9.79

QPPPKPFRRS

5.63

-10.45

-10.94

GQPPVPVRMQ

5.92

-10.98

-11.47
P53264

GFSSRPKFPF

9.19

-7.16

-7.65

SSRPKFPFEY

9.58

-6.16

-6.65

YGFSSRPKFP

10.05

-3.29

-3.78
P46956

SDKNAPSVPQ

11.16

-4.32

-4.81

NAPSVPQVDA

12.44

-5.05

-5.54
Q08989

PPPPDEKGRG

10.72

-4.78

-5.27

PPPPPDEKGR

11.69

-5.80

-6.29

GPPPPPPPPD

11.84

-6.59

-7.08
Q7LHG5

CLPNFPIQPS

9.18

-7.63

-8.12

PNFPIQPSLT

9.68

-6.08

-6.57

NFPIQPSLTF

10.13

-6.88

-7.37
P00812

GLNKDVPHCP

9.87

-6.42

-6.91

LNKDVPHCPE

10.30

-5.70

-6.19

DVPHCPESLK

10.40

-6.71

-7.20
P37370

SAPKVPQNRP

8.00

-8.89

-9.38

NRPHMPSVRP

8.17

-8.15

-8.64

KVPQNRPHMP

8.24

-7.72

-8.21
P40187

GNPSPPIYKK

9.84

-6.13

-6.62

DEPLNLPNNS

11.95

-7.05

-7.54

EPLNLPNNSA

11.98

-6.72

-7.21
P11792

IPPPFKPHLV

7.50

-8.03

-8.52

PPPFKPHLVS

9.85

-5.58

-6.07

PFKPHLVSET

10.87

-2.62

-3.11
P47977

NPFLPSAHLN

9.66

-5.24

-5.73

PQLMNPFLPS

10.85

-6.91

-7.40

MNPFLPSAHL

11.34

-6.82

-7.31
P40453

PDLPIRLRKR

5.44

-10.78

-11.27

KPPDLPIRLR

7.99

-10.74

-11.23

WKPPDLPIRL

9.00

-9.35

-9.84

 


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