ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-27.PDB
Scoring matrix: BUD14_1SEM-27_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 17.59
Foldx random average score for Saccharomyces cerevisiae: 17.136

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1758505
Proteins after disorder filtering: 4693
 Total fragments: 126150
Proteins after pattern filtering: 2302
 Total fragments: 19942
Proteins after MINT filtering: 12
 Total fragments: 176


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

17.59

-2.49

0.00

Best peptides

FKRRMRRRR

0.00

-2.06

0.43

         
Interactors      
P13186

EPLPEREPP

11.85

-3.69

-1.20

LPEREPPTY

12.12

-3.87

-1.38

SSIPMSPNY

13.17

-2.48

0.01

Q12276

LPSRKPKRG

7.43

-4.65

-2.16

FGRRPSTTP

8.79

-4.95

-2.46

SGTRPKILP

9.49

-2.14

0.35

P38853

MDVPTDTPT

13.68

-3.93

-1.44

SNKPFDTPT

13.98

-2.40

0.09

LDLATPVTP

14.47

-4.49

-2.00

P40095

VLPPPRSPN

11.27

-3.39

-0.90

NRIPVLPPP

11.66

-2.78

-0.29

PPPRSPNRP

11.87

-3.09

-0.60

P53858

EPNRPVSMS

12.22

-5.44

-2.95

LSTPRVKPD

12.31

-4.36

-1.87

STPRVKPDS

12.58

-2.87

-0.38

P42073

LNKRPPREP

7.57

-5.25

-2.76

NKRPPREPI

8.17

-4.34

-1.85

RPPREPIEF

10.50

-5.57

-3.08

P40036

IELPPLSPK

12.48

-3.60

-1.11

PPLSPKSTV

14.67

-3.11

-0.62

ELPPLSPKS

15.68

-3.83

-1.34

Q03016

LPSRTPKKG

10.32

-4.38

-1.89

SPANPKILP

11.63

-4.38

-1.89

QQLPSRTPK

11.67

-3.92

-1.43

Q07807

NPIPVKMPK

9.79

-4.05

-1.56

MFMPPPPLS

11.67

-3.94

-1.45

FPFAYPNPM

12.14

-5.30

-2.81

P40187

GNPSPPIYK

13.03

-3.86

-1.37

ENGNPSPPI

13.33

-1.98

0.51

NPSPPIYKK

13.46

-3.12

-0.63

P39960

LINNPATPN

13.01

-3.17

-0.68

MLINNPATP

13.99

-3.11

-0.62

IKFFDPTLP

14.05

-1.13

1.36

P26570

YSTPLNSPG

13.99

-3.37

-0.88

WSDPTDSPN

14.00

-3.59

-1.10

PKSPILKTN

14.00

-3.00

-0.51

 


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