ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-20.PDB
Scoring matrix: BUD14_1SEM-20_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.72
Foldx random average score for Saccharomyces cerevisiae: 16.753

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1582709
Proteins after disorder filtering: 4512
 Total fragments: 69487
Proteins after pattern filtering: 2007
 Total fragments: 7372
Proteins after MINT filtering: 13
 Total fragments: 61


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.72

-2.95

0.00

Best peptides

FRFFFGMWF

0.00

-4.22

-1.27

         
Interactors      
P13186

SSIPMSPNY

13.04

-4.30

-1.35

PMSPNYGNQ

14.67

-3.18

-0.23

IPLTPLATN

15.60

-1.08

1.87

Q12276

RRPSTTPSH

12.96

-2.09

0.86

DPPQQLPSR

14.91

-4.02

-1.07

SPQRPLSGQ

14.97

-3.36

-0.41

P38853

NKPFDTPTI

13.71

-3.59

-0.64

TPVTPTSHQ

14.73

-2.54

0.41

PFDTPTIQK

14.89

-2.64

0.31

P41818

PKTPYQGAV

15.24

-3.15

-0.20

P40095

LPPPRSPNR

10.81

-5.88

-2.93

PRSPNRPTL

12.62

-3.63

-0.68

FPDSPSSSS

15.80

-2.79

0.16

P53858

YLPEFEPNR

11.01

-5.41

-2.46

KPSPPSSKL

12.53

-6.47

-3.52

PNRPVSMSF

13.73

-3.54

-0.59

P42073

PREPIEFDL

11.82

-3.62

-0.67

NKRPPREPI

13.41

-7.32

-4.37

P40036

LPTTPGIRS

10.79

-2.52

0.43

IELPPLSPK

15.06

-4.78

-1.83

ELPPLSPKS

15.49

-2.79

0.16

Q03016

LFSPANPKI

14.56

-4.65

-1.70

DPPQQLPSR

14.91

-4.02

-1.07

SRPSTSPAS

15.15

-1.89

1.06

Q07807

PFAYPNPMM

13.06

-4.96

-2.01

NPIPVKMPK

13.22

-4.12

-1.17

FRPSNNPAA

13.34

-3.81

-0.86

P40187

NPSPPIYKK

14.10

-5.01

-2.06

DEPLNLPNN

15.18

-3.58

-0.63

PLNLPNNSA

15.67

-4.48

-1.53

P39960

NPATPNQKM

13.25

-3.43

-0.48

DPTLPASNS

14.47

-5.05

-2.10

FFDPTLPAS

15.62

-2.65

0.30

P26570

STPLNSPGL

13.25

-4.05

-1.10

PLNSPGLSK

13.50

-3.03

-0.08

PSTPSKPNL

16.18

-3.23

-0.28

 


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