ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-11.PDB
Scoring matrix: BUD14_1SEM-11_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.65
Foldx random average score for Saccharomyces cerevisiae: 11.615

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221199
Proteins after random average filtering: 7178
 Total fragments: 1181267
Proteins after disorder filtering: 4473
 Total fragments: 60969
Proteins after pattern filtering: 2093
 Total fragments: 10065
Proteins after MINT filtering: 12
 Total fragments: 91


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.65

-0.93

0.00

Best peptides

FRPRFPM

0.00

-1.94

-1.01

         
Interactors      
P13186

APSYVPN

8.38

-3.16

-2.24

IPMSPNY

9.29

-2.30

-1.37

NIPLTPL

9.84

-2.86

-1.93

Q12276

LPSRKPK

8.55

-3.91

-2.99

SPQRPLS

9.64

-2.30

-1.37

ASPQRPL

9.94

-2.41

-1.49

P38853

PFDTPTI

11.44

-2.45

-1.53

P40095

IPVLPPP

7.33

-6.24

-5.32

SPNRPTL

8.69

-1.84

-0.92

PRSPNRP

8.87

-3.90

-2.97

P53858

PRVKPDS

8.19

-4.10

-3.17

STPRVKP

8.55

-1.07

-0.15

YLPEFEP

9.53

-3.30

-2.38

P42073

RPPREPI

8.13

-3.38

-2.46

KRPPREP

8.80

-5.88

-4.96

PPREPIE

9.39

-4.09

-3.17

P40036

LPTTPGI

10.89

-4.46

-3.54

PPLSPKS

11.48

-2.84

-1.91

Q03016

KPSRPST

8.02

-1.85

-0.93

KPQTPIL

9.16

-3.50

-2.58

IPLLTPI

9.56

-2.85

-1.93

Q07807

IPVKMPK

7.37

-4.72

-3.79

FMPPPPL

7.49

-6.76

-5.84

FPFAYPN

7.67

-4.75

-3.83

P40187

NPSPPIY

9.70

-2.37

-1.45

PLNLPNN

10.01

-3.67

-2.75

GNPSPPI

10.66

-3.02

-2.09

P39960

NPATPNQ

10.53

-2.68

-1.76

DPTLPAS

10.75

-3.19

-2.26

P26570

TPSKPNL

8.96

-2.33

-1.41

EPKSPIL

10.35

-2.50

-1.58

STPLNSP

10.67

-1.90

-0.97

 


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