ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-1.PDB
Scoring matrix: BUD14_1SEM-1_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.35
Foldx random average score for Saccharomyces cerevisiae: 22.441

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7178
 Total fragments: 1815715
Proteins after disorder filtering: 4708
 Total fragments: 156137
Proteins after pattern filtering: 2309
 Total fragments: 22744
Proteins after MINT filtering: 12
 Total fragments: 189


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.35

-2.28

0.00

Best peptides

RPRMWYMFRY

0.00

-8.01

-5.73

         
Interactors      
P13186

RPPIPAALPP

10.68

-7.12

-4.84

IPLTPLATNT

12.02

-5.56

-3.28

IPAALPPSDM

12.18

-6.67

-4.39

Q12276

DPPQQLPSRK

10.35

-6.50

-4.22

RPSTTPSHVV

11.22

-5.91

-3.63

SPQRPLSGQN

11.58

-5.26

-2.98

P38853

KPFDTPTIQK

12.07

-7.36

-5.08

VPTDTPTPRN

12.12

-6.77

-4.49

LDLATPVTPT

14.33

-2.45

-0.17

P40095

IPVLPPPRSP

11.15

-8.06

-5.78

PPSSTFPDSP

11.55

-7.33

-5.05

PPPRSPNRPT

11.99

-5.86

-3.58

P53858

IDSMTPDSPV

11.04

-2.63

-0.35

TPRVKPDSQG

12.52

-5.63

-3.35

LPEFEPNRPV

12.76

-5.38

-3.10

P42073

RPPREPIEFD

10.70

-6.16

-3.88

LNKRPPREPI

14.14

-1.48

0.80

KRPPREPIEF

18.03

2.19

4.47

P40036

LPPLSPKSTV

13.03

-5.71

-3.43

PPLSPKSTVP

14.31

-6.16

-3.88

IELPPLSPKS

15.01

-4.36

-2.08

Q03016

TDNIPLLTPI

9.99

-3.64

-1.36

DPPQQLPSRT

11.02

-5.83

-3.55

RPSTSPASSS

11.85

-5.67

-3.39

Q07807

NPMMFMPPPP

10.35

-7.67

-5.39

RPSNNPAAVG

10.64

-6.11

-3.83

FPFAYPNPMM

10.85

-6.96

-4.68

P40187

EPLNLPNNSA

13.94

-3.95

-1.67

MDEPLNLPNN

14.35

-2.59

-0.31

ENGNPSPPIY

15.86

1.78

4.06

P39960

NPATPNQKMR

11.52

-6.85

-4.57

FDPTLPASNS

14.55

-2.15

0.13

NNPATPNQKM

17.26

-0.70

1.58

P26570

TPLNSPGLSK

12.83

-5.32

-3.04

TPSKPNLEVN

13.85

-4.41

-2.13

PDPSTPSKPN

14.68

-2.66

-0.38

 


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