ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-4.PDB
Scoring matrix: BUD14_1GCQ-4_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 16.14
Foldx random average score for Saccharomyces cerevisiae: 17.766

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7177
 Total fragments: 1494441
Proteins after disorder filtering: 4586
 Total fragments: 122793
Proteins after pattern filtering: 2306
 Total fragments: 22888
Proteins after MINT filtering: 13
 Total fragments: 198


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

16.14

9.99

0.00

Best peptides

RGPRWHPKMW

0.00

1.10

-8.89

         
Interactors      
P13186

RNSSIPMSPN

9.21

-2.90

-12.89

RPPIPAALPP

9.40

-1.89

-11.88

QQEPLPEREP

10.44

0.27

-9.72

Q12276

QQLPSRKPKR

7.79

-0.08

-10.07

RPSTTPSHVV

9.70

1.28

-8.71

PPQQLPSRKP

10.20

-2.38

-12.37

P38853

VPTDTPTPRN

11.49

0.82

-9.17

ASAPSPAPKD

11.78

2.73

-7.26

TSNKPFDTPT

12.82

0.89

-9.10

P41818

PKTPYQGAVD

13.34

3.06

-6.93

P40095

IPVLPPPRSP

9.38

-1.24

-11.23

PPPRSPNRPT

9.85

-0.77

-10.76

RSPNRPTLSD

10.17

1.52

-8.47

P53858

PKPSPPSSKL

10.63

-0.93

-10.92

FLSTPRVKPD

11.48

-1.90

-11.89

IDSMTPDSPV

12.50

-0.43

-10.42

P42073

NKRPPREPIE

9.23

1.74

-8.25

RPPREPIEFD

9.92

-1.67

-11.66

LNKRPPREPI

15.19

1.89

-8.10

P40036

FKIELPPLSP

12.81

-0.23

-10.22

SLPTTPGIRS

16.41

2.41

-7.58

PPLSPKSTVP

16.74

-2.84

-12.83

Q03016

QQLPSRTPKK

7.96

0.04

-9.95

TSLFSPANPK

11.02

0.89

-9.10

TKPSRPSTSP

11.96

0.91

-9.08

Q07807

PMMFMPPPPL

9.38

-1.03

-11.02

TPNPIPVKMP

10.21

0.97

-9.02

NSPFPFAYPN

10.30

1.00

-8.99

P40187

NGNPSPPIYK

10.30

0.83

-9.16

GNPSPPIYKK

11.15

-2.01

-12.00

PLNLPNNSAH

14.10

0.82

-9.17

P39960

NPATPNQKMR

8.78

1.55

-8.44

NNPATPNQKM

9.48

0.33

-9.66

IKFFDPTLPA

10.28

0.91

-9.08

P26570

PDPSTPSKPN

11.47

0.62

-9.37

TPSKPNLEVN

12.91

3.48

-6.51

TAYSTPLNSP

13.13

1.68

-8.31

 


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