ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-20.PDB
Scoring matrix: BUD14_1GCQ-20_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 18.31
Foldx random average score for Saccharomyces cerevisiae: 17.014

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1448124
Proteins after disorder filtering: 4406
 Total fragments: 56855
Proteins after pattern filtering: 1845
 Total fragments: 5838
Proteins after MINT filtering: 12
 Total fragments: 48


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

18.31

-3.12

0.00

Best peptides

MRFFIGMRW

0.00

-8.44

-5.32

         
Interactors      
P13186

SSIPMSPNY

16.14

-4.70

-1.58

PMSPNYGNQ

16.18

-4.18

-1.06

FKAPSYVPN

16.19

-4.30

-1.18

Q12276

RRPSTTPSH

12.58

-3.24

-0.12

QQLPSRKPK

13.72

-4.40

-1.28

SPQRPLSGQ

13.77

-3.52

-0.40

P38853

NKPFDTPTI

13.67

-3.96

-0.84

TPVTPTSHQ

14.83

-2.96

0.16

PFDTPTIQK

15.63

-2.16

0.96

P40095

LPPPRSPNR

12.73

-7.08

-3.96

PRSPNRPTL

13.48

-4.68

-1.56

SPNRPTLSD

15.84

-3.67

-0.55

P53858

KPSPPSSKL

12.82

-6.61

-3.49

YLPEFEPNR

13.68

-4.69

-1.57

PRVKPDSQG

14.40

-4.23

-1.11

P42073

PREPIEFDL

13.64

-5.25

-2.13

NKRPPREPI

14.18

-5.49

-2.37

P40036

LPTTPGIRS

11.32

-4.24

-1.12

KSLPTTPGI

14.89

-4.39

-1.27

ELPPLSPKS

16.09

-4.35

-1.23

Q03016

SRPSTSPAS

14.71

-3.14

-0.02

DPPQQLPSR

14.78

-4.93

-1.81

QLPSRTPKK

14.87

-5.20

-2.08

Q07807

PFAYPNPMM

14.16

-6.45

-3.33

NPIPVKMPK

14.46

-5.36

-2.24

FRPSNNPAA

15.10

-3.34

-0.22

P40187

NPSPPIYKK

13.94

-5.54

-2.42

P39960

NPATPNQKM

13.57

-4.58

-1.46

PATPNQKMR

15.83

-4.88

-1.76

FFDPTLPAS

16.02

-2.98

0.14

P26570

PLNSPGLSK

13.74

-2.60

0.52

VPDPSTPSK

14.75

-2.89

0.23

PKSPILKTN

16.01

-3.68

-0.56

 


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