ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-28.PDB
Scoring matrix: BUD14_1CKB-28_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 24.54
Foldx random average score for Saccharomyces cerevisiae: 19.179

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7178
 Total fragments: 1678728
Proteins after disorder filtering: 4393
 Total fragments: 72335
Proteins after pattern filtering: 2073
 Total fragments: 10358
Proteins after MINT filtering: 12
 Total fragments: 121


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

24.54

-0.46

0.00

Best peptides

RRKMWRNKRV

0.00

-2.74

-2.28

         
Interactors      
P13186

SIPMSPNYGN

13.84

-5.53

-5.07

NIPLTPLATN

14.55

-2.67

-2.21

KAPSYVPNRV

15.09

-3.85

-3.39

Q12276

RRPSTTPSHV

10.12

-6.83

-6.37

RPSTTPSHVV

13.24

-3.97

-3.51

GRRPSTTPSH

15.47

-2.56

-2.10

P38853

KPFDTPTIQK

12.18

-4.94

-4.48

VPTDTPTPRN

12.28

-5.04

-4.58

ATPVTPTSHQ

17.14

-2.58

-2.12

P40095

RIPVLPPPRS

11.77

-7.44

-6.98

RSPNRPTLSD

13.42

-4.05

-3.59

VLPPPRSPNR

15.32

-5.06

-4.60

P53858

EPNRPVSMSF

14.74

-3.49

-3.03

LPEFEPNRPV

14.79

-6.91

-6.45

DPKPSPPSSK

15.79

-3.34

-2.88

P42073

KRPPREPIEF

12.93

-6.03

-5.57

RPPREPIEFD

14.71

-4.32

-3.86

PREPIEFDLN

16.43

-3.34

-2.88

P40036

LPPLSPKSTV

14.44

-6.45

-5.99

KIELPPLSPK

14.45

-6.28

-5.82

SKSLPTTPGI

16.00

-3.96

-3.50

Q03016

IPLLTPINSG

13.23

-3.48

-3.02

KHPPISSPSN

14.00

-5.23

-4.77

LPSRTPKKGN

14.01

-4.57

-4.11

Q07807

FPFAYPNPMM

12.26

-7.23

-6.77

MMFMPPPPLS

15.72

-6.24

-5.78

FRPSNNPAAV

16.02

-4.73

-4.27

P40187

MDEPLNLPNN

14.19

-6.34

-5.88

EPLNLPNNSA

14.62

-5.21

-4.75

PLNLPNNSAH

16.82

-5.93

-5.47

P39960

FFDPTLPASN

14.77

-3.30

-2.84

KFFDPTLPAS

16.29

-5.28

-4.82

NNPATPNQKM

16.37

-5.02

-4.56

P26570

PKSPILKTNN

14.53

-6.64

-6.18

EPKSPILKTN

15.17

-4.04

-3.58

MEPKSPILKT

15.59

-5.52

-5.06

 


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