ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-23.PDB
Scoring matrix: BUD14_1CKB-23_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.38
Foldx random average score for Saccharomyces cerevisiae: 11.080

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221199
Proteins after random average filtering: 7178
 Total fragments: 1404157
Proteins after disorder filtering: 4633
 Total fragments: 70307
Proteins after pattern filtering: 2090
 Total fragments: 11305
Proteins after MINT filtering: 12
 Total fragments: 95


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.38

-1.59

0.00

Best peptides

WPLFPWM

0.00

-4.80

-3.21

         
Interactors      
P13186

LPEREPP

7.23

-5.63

-4.04

PPIPAAL

7.42

-6.12

-4.53

QQAPLMP

7.77

-4.51

-2.92

Q12276

LPSRKPK

7.36

-4.61

-3.02

SPQRPLS

8.44

-3.69

-2.10

RPKILPK

8.74

-5.68

-4.09

P38853

NKPFDTP

8.04

-4.76

-3.17

LATPVTP

9.38

-4.38

-2.79

APSPAPK

10.74

-2.28

-0.69

P40095

PVLPPPR

6.63

-5.62

-4.03

NRIPVLP

6.85

-6.01

-4.42

LPPPRSP

7.70

-4.84

-3.25

P53858

LPEFEPN

7.47

-5.36

-3.77

DPKPSPP

8.31

-4.39

-2.80

PNRPVSM

8.71

-4.76

-3.17

P42073

RPPREPI

6.09

-5.07

-3.48

KRPPREP

8.29

-4.42

-2.83

PREPIEF

10.35

-2.73

-1.14

P40036

KSLPTTP

5.81

-6.87

-5.28

LPPLSPK

7.95

-5.44

-3.85

ELPPLSP

8.42

-4.51

-2.92

Q03016

IPLLTPI

6.09

-7.86

-6.27

LPSRTPK

7.54

-4.50

-2.91

KPSRPST

7.82

-3.96

-2.37

Q07807

MFMPPPP

6.46

-6.52

-4.93

FMPPPPL

7.38

-3.85

-2.26

PFPFAYP

7.71

-4.25

-2.66

P40187

EPLNLPN

6.20

-5.25

-3.66

PSPPIYK

8.77

-3.77

-2.18

NPSPPIY

8.97

-2.64

-1.05

P39960

PTLPASN

8.06

-5.78

-4.19

FFDPTLP

10.23

-2.58

-0.99

DPTLPAS

10.57

-3.80

-2.21

P26570

TPLNSPG

8.22

-5.06

-3.47

PSKPNLE

10.20

-4.11

-2.52

PSTPSKP

10.34

-4.11

-2.52

 


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