ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-21.PDB
Scoring matrix: BUD14_1CKB-21_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 15.91
Foldx random average score for Saccharomyces cerevisiae: 15.212

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199665
Proteins after random average filtering: 7178
 Total fragments: 1999426
Proteins after disorder filtering: 4543
 Total fragments: 90271
Proteins after pattern filtering: 1863
 Total fragments: 5261
Proteins after MINT filtering: 13
 Total fragments: 50


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

15.91

-0.80

0.00

Best peptides

RWRMGIPDMK

0.00

-0.29

0.51

         
Interactors      
P13186

PLTPLATNTH

10.33

-0.20

0.60

NIPLTPLATN

11.36

-1.47

-0.67

PMSPNYGNQS

13.06

-1.39

-0.59

Q12276

DPPQQLPSRK

11.40

-2.17

-1.37

RRPSTTPSHV

11.90

-2.51

-1.71

PQRPLSGQNV

14.10

-1.64

-0.84

P38853

PYVPSESSQT

8.73

-1.74

-0.94

APSPAPKDFS

10.78

-4.19

-3.39

NKPFDTPTIQ

11.23

-4.54

-3.74

P41818

PKTPYQGAVD

12.37

-1.86

-1.06

P40095

PRSPNRPTLS

11.54

-5.00

-4.20

STFPDSPSSS

12.48

-0.56

0.24

P53858

DPKPSPPSSK

10.65

-1.02

-0.22

STPRVKPDSQ

11.18

-3.84

-3.04

EFEPNRPVSM

11.85

-1.90

-1.10

P42073

PREPIEFDLN

6.53

-5.57

-4.77

KRPPREPIEF

7.38

-3.37

-2.57

RPPREPIEFD

14.93

-3.59

-2.79

P40036

KSLPTTPGIR

10.40

-3.30

-2.50

ELPPLSPKST

11.32

-1.79

-0.99

LPPLSPKSTV

12.54

-2.07

-1.27

Q03016

NTKPSRPSTS

10.73

-0.70

0.10

NIPLLTPINS

10.85

-3.04

-2.24

LFSPANPKIL

10.91

-1.90

-1.10

Q07807

NTPVFRPSNN

13.24

-1.62

-0.82

FRPSNNPAAV

13.32

-1.76

-0.96

PFAYPNPMMF

14.67

-5.66

-4.86

P40187

NGNPSPPIYK

11.17

-1.74

-0.94

DEPLNLPNNS

15.21

-2.71

-1.91

P39960

FFDPTLPASN

10.37

-2.02

-1.22

INNPATPNQK

11.10

-2.43

-1.63

PATPNQKMRD

15.15

-3.68

-2.88

P26570

PKSPILKTNN

12.43

-4.00

-3.20

PSTPSKPNLE

13.37

-3.05

-2.25

STPLNSPGLS

13.61

-4.94

-4.14

 


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