ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-20.PDB
Scoring matrix: BUD14_1CKB-20_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 21.45
Foldx random average score for Saccharomyces cerevisiae: 18.585

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206843
Proteins after random average filtering: 7178
 Total fragments: 1536702
Proteins after disorder filtering: 4556
 Total fragments: 62625
Proteins after pattern filtering: 1927
 Total fragments: 6103
Proteins after MINT filtering: 13
 Total fragments: 53


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

21.45

-1.81

0.00

Best peptides

MRKFFGNSF

0.00

-6.55

-4.74

         
Interactors      
P13186

IPLTPLATN

15.27

-3.71

-1.90

SSIPMSPNY

15.83

-5.90

-4.09

KAPSYVPNR

16.44

-4.50

-2.69

Q12276

RRPSTTPSH

14.37

-5.90

-4.09

QLPSRKPKR

16.59

-6.17

-4.36

DPPQQLPSR

17.03

-5.61

-3.80

P38853

NKPFDTPTI

17.23

-5.12

-3.31

LASAPSPAP

17.91

-6.28

-4.47

P41818

PKTPYQGAV

18.58

-6.04

-4.23

P40095

LPPPRSPNR

11.74

-7.55

-5.74

PRSPNRPTL

13.46

-5.59

-3.78

FPDSPSSSS

17.23

-4.71

-2.90

P53858

KPSPPSSKL

11.08

-8.33

-6.52

LKEDPKPSP

14.01

-7.94

-6.13

PNRPVSMSF

14.89

-5.11

-3.30

P42073

PREPIEFDL

14.49

-5.82

-4.01

NKRPPREPI

16.49

-9.71

-7.90

KRPPREPIE

17.05

-5.37

-3.56

P40036

LPTTPGIRS

13.57

-6.20

-4.39

ELPPLSPKS

17.19

-5.85

-4.04

IELPPLSPK

17.24

-7.50

-5.69

Q03016

KPSRPSTSP

13.79

-5.67

-3.86

LFSPANPKI

14.43

-6.25

-4.44

KHPPISSPS

16.26

-4.79

-2.98

Q07807

NTPVFRPSN

14.43

-5.99

-4.18

MPPPPLSAP

15.13

-9.30

-7.49

PFAYPNPMM

16.76

-7.64

-5.83

P40187

PLNLPNNSA

17.21

-5.26

-3.45

MDEPLNLPN

17.99

-4.10

-2.29

DEPLNLPNN

18.33

-5.33

-3.52

P39960

INNPATPNQ

16.32

-4.26

-2.45

DPTLPASNS

17.40

-6.43

-4.62

NPATPNQKM

17.81

-6.56

-4.75

P26570

STPLNSPGL

16.02

-7.76

-5.95

PLNSPGLSK

16.81

-4.99

-3.18

LWSDPTDSP

17.41

-5.51

-3.70

 


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