ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-12.PDB
Scoring matrix: BUD14_1CKB-12_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.34
Foldx random average score for Saccharomyces cerevisiae: 9.751

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214021
Proteins after random average filtering: 7178
 Total fragments: 1345121
Proteins after disorder filtering: 4620
 Total fragments: 84967
Proteins after pattern filtering: 2170
 Total fragments: 12596
Proteins after MINT filtering: 13
 Total fragments: 120


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.34

-1.48

0.00

Best peptides

WSMRRNRK

0.00

-2.73

-1.25

         
Interactors      
P13186

PSYVPNRV

4.77

-5.15

-3.67

NSSIPMSP

6.78

-4.40

-2.92

SIPMSPNY

7.26

-4.62

-3.14

Q12276

TRPKILPK

5.92

-5.53

-4.05

PSRKPKRG

6.46

-4.62

-3.14

LPSRKPKR

6.67

-3.73

-2.25

P38853

NKPFDTPT

8.84

-3.47

-1.99

ASAPSPAP

9.06

-2.73

-1.25

SNKPFDTP

9.23

-3.12

-1.64

P41818

PKTPYQGA

9.53

-2.42

-0.94

P40095

PPPRSPNR

6.25

-5.72

-4.24

PPRSPNRP

7.41

-2.64

-1.16

VLPPPRSP

7.60

-4.07

-2.59

P53858

PEFEPNRP

5.38

-5.12

-3.64

STPRVKPD

7.02

-4.65

-3.17

EDPKPSPP

7.35

-4.68

-3.20

P42073

RPPREPIE

6.58

-4.75

-3.27

KRPPREPI

7.33

-4.71

-3.23

NKRPPREP

8.32

-2.71

-1.23

P40036

PTTPGIRS

7.28

-4.00

-2.52

ELPPLSPK

8.90

-3.30

-1.82

LPPLSPKS

9.39

-3.99

-2.51

Q03016

ANPKILPK

6.04

-5.23

-3.75

LFSPANPK

6.27

-2.22

-0.74

LPSRTPKK

7.35

-3.72

-2.24

Q07807

VFRPSNNP

5.76

-4.01

-2.53

PIPVKMPK

5.92

-4.79

-3.31

PVFRPSNN

6.00

-4.91

-3.43

P40187

PSPPIYKK

6.93

-5.34

-3.86

MDEPLNLP

6.95

-2.59

-1.11

PLNLPNNS

7.73

-5.10

-3.62

P39960

NPATPNQK

7.42

-3.28

-1.80

PATPNQKM

8.11

-3.55

-2.07

FFDPTLPA

8.45

-4.23

-2.75

P26570

TPSKPNLE

6.40

-4.53

-3.05

MEPKSPIL

6.96

-5.16

-3.68

YSTPLNSP

7.27

-4.12

-2.64

 


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