ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-7.PDB
Scoring matrix: BEM1-D2_1SEM-7_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 14.68
Foldx random average score for Saccharomyces cerevisiae: 11.933

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3214177
Proteins after random average filtering: 7178
 Total fragments: 1462240
Proteins after disorder filtering: 4483
 Total fragments: 62130
Proteins after pattern filtering: 1960
 Total fragments: 8786
Proteins after MINT filtering: 9
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

14.68

0.55

0.00

Best peptides

WRHFFPWE

0.00

-4.49

-5.04

         
Interactors      
P38041

QPPQSPSF

9.82

-2.86

-3.41

PKPPSYPS

10.55

-3.14

-3.69

PSPVQPPQ

10.65

-3.43

-3.98

P21268

SKPISPPP

10.29

-3.98

-4.53

P11433

PSATPNME

10.01

-6.00

-6.55

P50090

TALPWSPE

10.67

-1.85

-2.40

VTPTLPPN

10.87

-3.97

-4.52

ALPWSPES

11.46

-2.16

-2.71

P32618

VPNLSPRL

8.29

-5.93

-6.48

NPVISPYS

8.90

-5.01

-5.56

TNPMHPQS

9.82

-3.20

-3.75

Q03497

FPSKNPLK

8.81

-4.61

-5.16

KVKPSKPE

9.26

-3.79

-4.34

KPKVKPSK

9.72

-4.26

-4.81

P39969

QPPKSPLL

7.64

-5.39

-5.94

VSPRRAPK

8.95

-3.75

-4.30

RRAPKPPS

9.30

-3.41

-3.96

P22224

STPTFPNA

11.60

-2.72

-3.27

TPTFPNAN

11.63

-4.22

-4.77

P35735

SPHFNPQS

10.06

-3.34

-3.89

ASPHFNPQ

10.53

-2.80

-3.35

 


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