ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-29.PDB
Scoring matrix: BEM1-D2_1SEM-29_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.75
Foldx random average score for Saccharomyces cerevisiae: 15.981

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1331422
Proteins after disorder filtering: 4015
 Total fragments: 44102
Proteins after pattern filtering: 1948
 Total fragments: 9886
Proteins after MINT filtering: 9
 Total fragments: 65


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.75

-2.63

0.00

Best peptides

RYPPKFPRWH

0.00

-12.94

-10.31

         
Interactors      
P38041

GRAPKPPSYP

10.88

-6.04

-3.41

CFKLVPPQPG

11.99

-9.12

-6.49

PKPPSYPSPV

13.91

-7.87

-5.24

P21268

LNLSKPISPP

13.45

-7.43

-4.80

LSKPISPPPS

14.42

-8.31

-5.68

SKPISPPPSL

15.42

-8.11

-5.48

P11433

SNPSATPNME

14.76

-7.25

-4.62

P50090

VTPTLPPNQH

10.34

-10.68

-8.05

ALPWSPESKN

15.34

-6.23

-3.60

P32618

EPSPKPSHKR

11.69

-8.33

-5.70

KVPAKEPSPK

11.71

-6.82

-4.19

EPAPLPSHYS

12.29

-8.31

-5.68

Q03497

NGKFIPSRPA

8.80

-12.47

-9.84

KPKVKPSKPE

10.06

-8.29

-5.66

SFPSKNPLKN

10.23

-8.36

-5.73

P39969

AQPPKSPLLN

8.40

-9.51

-6.88

RRAPKPPSYP

10.38

-8.02

-5.39

CFKLLPPQPG

10.76

-10.49

-7.86

P22224

MTPSTPTFPN

13.80

-11.03

-8.40

IFPSTPGTID

15.40

-9.04

-6.41

STPTFPNANG

15.82

-8.28

-5.65

P35735

PLASPHFNPQ

15.12

-6.06

-3.43

ASPHFNPQSS

15.47

-6.23

-3.60

 


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