ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-28.PDB
Scoring matrix: BEM1-D2_1SEM-28_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.08
Foldx random average score for Saccharomyces cerevisiae: 18.476

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1459236
Proteins after disorder filtering: 4114
 Total fragments: 48471
Proteins after pattern filtering: 1905
 Total fragments: 8283
Proteins after MINT filtering: 9
 Total fragments: 68


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.08

-3.83

0.00

Best peptides

RRRIFPRPRR

0.00

-8.63

-4.80

         
Interactors      
P38041

PPQSPSFNNR

11.64

-8.89

-5.06

KPPSYPSPVQ

15.03

-6.65

-2.82

KLVPPQPGSK

15.33

-9.20

-5.37

P21268

PISPPPSLKK

13.89

-8.90

-5.07

KPISPPPSLK

14.47

-9.75

-5.92

SKPISPPPSL

18.23

-6.52

-2.69

P11433

NSNPSATPNM

16.26

-5.91

-2.08

P50090

TPTLPPNQHR

10.60

-9.45

-5.62

TALPWSPESK

16.66

-5.22

-1.39

VTPTLPPNQH

17.30

-7.58

-3.75

P32618

EPSPKPSHKR

12.14

-10.75

-6.92

TPSTSPSGRR

12.38

-10.08

-6.25

VPNLSPRLSN

14.05

-7.57

-3.74

Q03497

LPPIPPTKSK

10.47

-10.22

-6.39

QTHAPTTPNR

11.60

-8.37

-4.54

KPSKPEAKSK

13.54

-9.30

-5.47

P39969

ALSPIPSPTR

12.16

-8.91

-5.08

PKSPLLNNTR

13.75

-8.75

-4.92

SPEENPITSM

14.74

-7.24

-3.41

P22224

TPSTPTFPNA

15.24

-8.78

-4.95

STPTFPNANG

15.81

-8.65

-4.82

FPSTPGTIDS

17.19

-7.58

-3.75

P35735

PHFNPQSSEK

16.93

-8.38

-4.55

SPHFNPQSSE

17.82

-6.16

-2.33

LASPHFNPQS

18.08

-7.38

-3.55

 


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