ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-23.PDB
Scoring matrix: BEM1-D2_1SEM-23_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 14.55
Foldx random average score for Saccharomyces cerevisiae: 11.168

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3221355
Proteins after random average filtering: 7178
 Total fragments: 1455267
Proteins after disorder filtering: 4592
 Total fragments: 58045
Proteins after pattern filtering: 1873
 Total fragments: 6137
Proteins after MINT filtering: 8
 Total fragments: 45


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

14.55

-2.32

0.00

Best peptides

RPLRPWM

0.00

-6.62

-4.30

         
Interactors      
P38041

RAPKPPS

7.69

-5.00

-2.68

SPGRAPK

8.19

-4.71

-2.39

SPVQPPQ

9.84

-3.76

-1.44

P21268

KPISPPP

9.72

-4.94

-2.62

P50090

TPTLPPN

9.82

-5.30

-2.98

P32618

PNLSPRL

8.80

-5.44

-3.12

EPIQPSS

9.18

-3.65

-1.33

NPMHPQS

9.41

-4.60

-2.28

Q03497

IPSRPAP

6.95

-5.63

-3.31

FPSKNPL

7.45

-4.86

-2.54

HKPKVKP

7.57

-5.43

-3.11

P39969

SPRRAPK

5.97

-4.92

-2.60

VSPRRAP

7.31

-5.12

-2.80

RAPKPPS

7.69

-5.00

-2.68

P22224

TPTFPNA

9.57

-3.79

-1.47

QSPMTPS

10.27

-5.26

-2.94

P35735

SPHFNPQ

9.01

-3.39

-1.07

ASPHFNP

10.90

-4.23

-1.91

 


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