ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-21.PDB
Scoring matrix: BEM1-D2_1SEM-21_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 19.53
Foldx random average score for Saccharomyces cerevisiae: 18.661

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7178
 Total fragments: 1838089
Proteins after disorder filtering: 4323
 Total fragments: 61093
Proteins after pattern filtering: 1488
 Total fragments: 3268
Proteins after MINT filtering: 7
 Total fragments: 20


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

19.53

-2.01

0.00

Best peptides

EEKMHRPMMR

0.00

-5.14

-3.13

         
Interactors      
P38041

QSNPTSPTKQ

15.01

-3.69

-1.68

PTSPTKQTFT

15.07

-4.70

-2.69

PQSPSFNNRY

16.00

-5.69

-3.68

P11433

SNPSATPNME

18.30

-4.34

-2.33

P50090

TALPWSPESK

18.22

-1.47

0.54

ALPWSPESKN

18.31

-5.02

-3.01

P32618

EPSPKPSHKR

11.66

-6.69

-4.68

TPSTSPSGRR

15.94

-4.34

-2.33

PIVPGNNTTL

16.07

-4.75

-2.74

Q03497

KVKPSKPEAK

14.96

-3.62

-1.61

THAPTTPNRT

15.56

-3.55

-1.54

TGLPGSPQVS

16.11

-2.85

-0.84

P39969

PKSPLLNNTR

13.94

-5.25

-3.24

LLPPQPGSKK

17.75

-5.02

-3.01

SPIPSPTRNS

18.08

-3.18

-1.17

P22224

PSTPTFPNAN

18.41

-3.46

-1.45

 


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