ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-2.PDB
Scoring matrix: BEM1-D2_1SEM-2_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.47
Foldx random average score for Saccharomyces cerevisiae: 19.076

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199821
Proteins after random average filtering: 7177
 Total fragments: 1539782
Proteins after disorder filtering: 4620
 Total fragments: 126875
Proteins after pattern filtering: 2314
 Total fragments: 22555
Proteins after MINT filtering: 9
 Total fragments: 158


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.47

4.00

0.00

Best peptides

DLWRPHRDNW

0.00

3.41

-0.59

         
Interactors      
P38041

SPGRAPKPPS

8.76

-2.57

-6.57

PPSYPSPVQP

11.93

-3.92

-7.92

ESPGRAPKPP

12.44

-4.58

-8.58

P21268

LNLSKPISPP

11.74

-5.19

-9.19

SKPISPPPSL

11.90

-2.86

-6.86

PISPPPSLKK

11.91

-3.34

-7.34

P11433

NSNPSATPNM

12.36

-1.41

-5.41

TNSNPSATPN

16.21

-0.80

-4.80

SNPSATPNME

17.28

-0.60

-4.60

P50090

ALPWSPESKN

11.90

-3.17

-7.17

ASTALPWSPE

13.11

-0.98

-4.98

VTPTLPPNQH

14.16

-4.20

-8.20

P32618

DVPIVPGNNT

9.76

-3.05

-7.05

VPAKEPSPKP

10.47

-4.43

-8.43

TPSTSPSGRR

10.82

-3.18

-7.18

Q03497

FIPSRPAPKP

9.16

-4.15

-8.15

IPSRPAPKPP

9.33

-7.69

-11.69

HKQHKPKVKP

10.77

-4.41

-8.41

P39969

SPRRAPKPPS

8.37

-4.14

-8.14

VSPRRAPKPP

8.53

-3.99

-7.99

SPAQPPKSPL

9.90

-3.50

-7.50

P22224

NGYQSPMTPS

13.16

-2.67

-6.67

SPMTPSTPTF

13.25

-1.09

-5.09

QSPMTPSTPT

13.30

-1.21

-5.21

P35735

PLASPHFNPQ

10.47

-2.52

-6.52

SPHFNPQSSE

14.27

-1.29

-5.29

ASPHFNPQSS

16.63

-1.46

-5.46

 


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